1. Drug resistance in the mycobacterium tuberculosis to isoniazid is seen due to which of the following:TransductionMutationTransformationConjugationQuestion 1 of 20 2. The therapeutic advantage that penicillin V has over penicillin G isSlower renal excretionGreater resistance to penicillinaseBroader antibacterial spectrumMore reliable oral absorptionQuestion 2 of 20 3. Comparison of efficacy of a new drug B with an existing drug A is done in which phase of clinical trialsPhase IIIPhase IVPhase IIPhase IQuestion 3 of 20 4. Drug of choice in pregnancy induced hypertension isDiureticLosartanmethyldopaAmlodipineQuestion 4 of 20 5. Which of the following statements is not true regarding sulphonamidesSulphonamide administration to newborn may cause kernicterusCrystalluria can occur with sulphonamide administrationSulphasalazine is absorbed well from GITSulphonamides are of value in treatment of infections due to nocardia speciesQuestion 5 of 20 6. Clindamycin acts by inhibitingInhibition of cell wall synthesisDNA gyraseProtein synthesisLysosomal enzymesQuestion 6 of 20 7. Which of the following condition Thiazide diuretics are not usedCongestive Heart FailureHypertensionHyperlipidemiaIdiopathic hypercalciurea with nephrocalcinosisQuestion 7 of 20 8. Most common cause of Mobius syndrome is use of which of the following drug in pregnancyMethotrexatedinoprostoneThalidomideMisoprostolQuestion 8 of 20 9. Which of the following is the most serious and life threatening blood dyscrasia caused with a drugMegaloblastic anemiaThrombocytopeniaHemolytic anemiaAplastic anemiaQuestion 9 of 20 10. Which of the following action is ascribed to Delta type of opiod receptorsReduced intestinal motilitySupraspinal analgesiaRespiratory depressionEuphoriaQuestion 10 of 20 11. Alcohol when ingested is eliminated by:First pass metabolismRedistributionZero order kineticsEnterohepatic circulationQuestion 11 of 20 12. All of these drugs can be used in the treatment of post-menopausal osteoporosis EXCEPTThyroxineCalciumAlendronateTeriparatideQuestion 12 of 20 13. A patient has subclinical folate deficiency. All of the following drugs can precipitate megaloblastic anemia in this patient exceptAlcoholChloroquinePhenytoinSulfasalzineQuestion 13 of 20 14. Which drug causes least hepatic failure:PyrazinamideINHRifampicinStreptomycinQuestion 14 of 20 15. The drug not used for analgesia in a patient of head injury ismorphineAcetaminophenRofecoxibNSAIDSQuestion 15 of 20 16. All are true about heparin exceptIt is a heterogenous mixture of sulphated polypeptidesPotentiates the action of antithrombin IIIInhibited by protamine sulphateCan cause thrombocytopeniaQuestion 16 of 20 17. Penicillin induced hypersensitivity is:Type BType AType DType CQuestion 17 of 20 18. Which drug should not be given in pregnancyMethyldopaLabetalolHydralazineACE inhibitorsQuestion 18 of 20 19. Xenon anaesthesia all are true exceptMinimal cardiovascular side effectsSlow induction and recoveryNon explosiveLow blood solubilityQuestion 19 of 20 20. All of the following drugs have activity against hepatitis B virus exceptZidovudineEmtricitabineLamivudineTelbivudineQuestion 20 of 20 Loading...