1. Widest spectrum aminoglycoside is Framycetin Netimicin Amikacin Streptomycin 2. Statins are used for cholesterol reduction, It antagonises HMG COA reductase. What kind of inhibition is seen Competitive Non competitive Functional Non specific 3. Fluconazole differs from ketaconazole in that It is more potent inhibitor of drug metabolism It is unlikely to produce anti- androgenic side effects It is not effective in cryptococcal meningitis It is not active by the oral route 4. Tetracycline acts by inhibiting protein synthesis at: 50 S ribosome Mitochondria Golgi body 30 S ribosome 5. The following causes increased intraocular pressure Barbiturate Althesin Thiopentone Ketamine 6. Two drugs having opposite action on different receptors in which type of antagonism Competitive antagonism Physiological antagonism Non competitive antagonism Physical antagonism 7. Fluconazole resistant candidiasis in a HIV positive patient is treated by Ketoconazole Amphotericin B Clotrimazole Nystatin 8. Most effective treatment for severe malaria is Primaquine Artesunate Quinine Chloroquine 9. When comparing opioids with NSAIDS which of the following is correct? NSAIDS cause more constipation. Opioids impair gastric motility to a greater extent. NSAIDS cause more drowsiness Opioids predispose to more bleeding. 10. General anesthetics can do all of the following EXCEPT stimulate medullary centers. produce delirium. produce a state of unconsciousness. reduce perception of painful stimuli. 11. The group of antibiotics which possess additional antiinflammatory and immunomodulatory activities is Macrolides Fluroquinolones Polypeptide antibiotics Tetracyclines 12. Design of the study aim to assess the maximum tolerable dose of a new drug is best described as Case control study Phase II Randomised control trial Phase I trial Phase III Randomised control trial 13. Aminoglycosides cause all of the following except Ototoxicity Nephrotoxicity neuromuscular blockade Cardiotoxicity 14. Which drug would treat both dermatophysis and candida infections Griseofulvin Tolnaftate Nystatin Ketoconazole 15. Bacteriostatic antitubercular drug is Ethambutol Rifampin INH Pyrazinamide 16. Which of the following action is ascribed to Delta type of opiod receptors Euphoria Reduced intestinal motility Supraspinal analgesia Respiratory depression 17. A patient on aspirin will have increase in Clotting time Activated partial thromboplastin time Prothrombin time Bleeding time 18. One of the following is not an antifungal agent Clofazimine Ketoconazole Ciplopirox Undecyclenic acid 19. Phocomelia is best described as Defect in development of flat bones Defect in development of long bones Defect in cartilage replacement by bones Defect in intramembranous ossification 20. Which of the following antibiotic is used in the treatment of clostridium difficile associated diarrhea Piperacillin Ciprofloxacin Clindamycin Metronidazole Loading … Question 1 of 20
