1. True about aminoglycoside is all except Excreted unchanged in urine Teratogenic Are bacteriostatic Distributed only extracellularly 2. Ketamine should be avoided in Asthamatic The presence of increased arterial pressure Hypovolemic shock Pregnancy 3. 28 yrs old female on oral contraceptives was given tetracycline for treatment of chronic periodontitis by a dentist. After 2 months she became preganant.What is the reason of contraceptive failure? Tetracycline induces metabolism of estrogen tetracycline inhibits metabolism of estrogen Tetracycline inhibits enterohepatic circulation causing increased excretion of estrogen tetracycline displaces estrogen from plasma protein 4. Which anti tubercular causes reversible Red Orange Urine: Rifampicin Ethambutol Pyrazinamide Isoniazid 5. Long-term use of aspirin in rheumatoid arthritis is limited by its propensity to cause Metabolic acidosis Salicylism Gastric mucosal damage Hypersensitivity reactions 6. Drug inhibiting cell wall synthesis: Vancomycin Clindamycin Erythromycin Azathioprine 7. Of the following, aspirin does not cause Acid base disturbance Occult bleeding Nausea and vomiting Suppression of the cough reflex 8. The activity of procaine is terminated by Metabolism in the liver and by pseudocholinesterase in the plasma Metabolism in the liver only Storage in the adipose tissues Elimination by kidney 9. Morphine a powerful opioid analgesic drug shuld be avoided in all of the following conditions except Pancreatitis Bronchial asthma Left ventricular failure Constipation 10. All of the following statements about pain are correct except Naloxane is a non competitive antagonist and irreversibly opposes the opioids Analgesia is associated with ‘u’ and ‘k’ receptors Dysphoria is associated with ‘k’ receptors NSAIDS benefit by preventing prostaglandin synthesis 11. Antifungal used as cancer therapeutic agent is Flucytosine Voriconazole Terbinafine Nystatin 12. Drug of choice for pseudomembranous enterocolitis Linezolid cephalexin clindamycin Oral vancomycin 13. Which one of the following inhalational agents is the induction agents of choice in children Methoxyflurane Desflurane Isoflurane Sevoflurane 14. Drug resistance in the mycobacterium tuberculosis to isoniazid is seen due to which of the following: Conjugation Transduction Transformation Mutation 15. A patient without prior medication breathes a gas mixture consisting of 50% N2O and 50% O2 by volume .Which of the following effects would be expected Surgical anaesthesia Excitation Analgesia Respiratory arrest 16. Rofecoxib was withdrawn due to Renal complication Gastric ulcer liver adenoma Ischemic heart disease 17. The ratio of median lethal dose to median effective dose is the Therapeutic index Anaethetic ratio Mortality index Morbidity index 18. Fluconazole resistant candidiasis in a HIV positive patient is treated by Clotrimazole Amphotericin B Nystatin Ketoconazole 19. All of the following are drugs causing SLE or SLE like reaction except Isoniazid Sulphonamide Hydralazine Penicillin 20. Which one of the following skeletal muscle relaxants causes pain on injection Vecuronium pancuronium Rocuronium Succinyl choline Loading … Question 1 of 20