1. Cyclooxygenase enzyme is not inhibited by Aspirin Warfarin Diclofenac Phenylbutazone 2. Shortest acting opioid is Remifentanyl Morphine Fentanyl Sufentanyl 3. Patient is suffering from atherosclerosis. Which of the following is the most beneficial drug for prevention of stroke in this patient Aspirin Warfarin Digoxin Low dose sub cutaneous heparin 4. Cross resistance of isoniazid is seen with Ethionamide Cycloserine Rifampicin Ethambutol 5. Drug resistance in Staphylococcus aureus is most commonly acquired by Transformation Mutation Transduction Conjugation 6. All of the following statements about opioids is correct except Partial agonists are free from classic opioid aderse effects Ethoheptazine is similar to pethidine chemically Pentazocine shows withdrawl symptoms in opioid dependent patients Pentazocine and buprenophrine are both complex action opioids 7. Buprenorphine is Pure agonist Pure antagonist Partial agonist None 8. 28 yrs old female on oral contraceptives was given tetracycline for treatment of chronic periodontitis by a dentist. After 2 months she became preganant.What is the reason of contraceptive failure? Tetracycline inhibits enterohepatic circulation causing increased excretion of estrogen Tetracycline induces metabolism of estrogen tetracycline inhibits metabolism of estrogen tetracycline displaces estrogen from plasma protein 9. Angiotensin II causes all except Stimulates aldosterone release Vasodilation Stimulates release of ADH Increases thirst 10. First generation cephalosporin is Cefipime Ceftazidime Cefadrox Cefotaxime 11. Loading dose depends upon Rate of administration Half life Volume of distribution Clearance 12. Statins are used for cholesterol reduction, It antagonises HMG COA reductase. What kind of inhibition is seen Competitive Non specific Non competitive Functional 13. All of the following drugs have activity against hepatitis B virus except Emtricitabine Telbivudine Zidovudine Lamivudine 14. Multiple drug resistance is transferred through conjugation transduction mutation Transformation 15. One of the following is not an antifungal agent Ciplopirox Ketoconazole Undecyclenic acid Clofazimine 16. Which of the following drugs inhibit an enzyme in the prostaglandin synthesis Aprotinin Alteplase Aminocaproic acid Aspirin 17. Bacteriostatic antitubercular drug is Pyrazinamide Ethambutol Rifampin INH 18. Which of the following drug inhibits cell wall synthesis Doxycycline Aminoglycosides Cephalosporin Erythromycin 19. When comparing opioids with NSAIDS which of the following is correct? NSAIDS cause more constipation. NSAIDS cause more drowsiness Opioids impair gastric motility to a greater extent. Opioids predispose to more bleeding. 20. When 2 drugs A and B are compared false statement is If drug A produces more effect than maximum tolerable dose of drug B then A is more efficacious than B If 1 mg of drug A produces same effect as 3 mg of drug B then A is more potent than B If 1 mg of drug A has higher degree of same effect than 1 mg of drug B then A is more efficacious than B Dose and drug efficacy are not related Loading … Question 1 of 20
