1. Osteomalacia is adverse effect of:carbamazepineValproic acidPhenytoinPrimidoneQuestion 1 of 20 2. The most potent analgesic agent isSufentanilfentanylAlfentanilRemifentanilQuestion 2 of 20 3. Status epilepticus is managed best with the use of which of the following drugs?Rectal diazepamIntravenous diazepamIntravenous phenytoin sodiumIntramuscular phenobarbitoneQuestion 3 of 20 4. Oral contraceptive (OCP)failure by rifampicin is due toIncreased chances of ovulation due to rifampicinIncreased metabolism of OCPsIncreased binding of OCPs by rifampicin and reduced free drug concentrationDecreased absorption of OCPsQuestion 4 of 20 5. Which of the following statements is not true regarding sulphonamidesSulphonamides are of value in treatment of infections due to nocardia speciesSulphasalazine is absorbed well from GITCrystalluria can occur with sulphonamide administrationSulphonamide administration to newborn may cause kernicterusQuestion 5 of 20 6. The concentration of sodium ions in the standard WHO oral rehydration solution is110m moles/L60m moles/L90m moles/L40m moles/LQuestion 6 of 20 7. Therapeutic index is a measure ofEfficacypotencyDrug safetyBioavailabilityQuestion 7 of 20 8. Which drug used in the treatment of seizures causes Hirsutism, osteomalacia, acne and gingival enlargement:Sodium valproateImipraminePhenytoinCarbamazepineQuestion 8 of 20 9. All are vasodilators exceptLidocaineCocaineProcaineChlorprocaineQuestion 9 of 20 10. Which is not a second generation antihistaminicTerfenadineCyclizineLoratidineAcrivastatineQuestion 10 of 20 11. Botulinum toxin acts bySecretion of AchInhibits Ach releaseMuscle nerve blockSynthesis of AchQuestion 11 of 20 12. Aminoglycosides cause all of the following exceptneuromuscular blockadeOtotoxicityCardiotoxicityNephrotoxicityQuestion 12 of 20 13. Filgrastim isUsed in neutropeniaAntifilarialAntianemiaAntimalarialQuestion 13 of 20 14. Which of the following is not true about MetforminInhibits cellular respirationExcreted unchanged in urineCan be given in decompensated heart failureDecreases hepatic glucose formationQuestion 14 of 20 15. Which of the following antiarrhythmic agent does not belong to class 1CEncainideFlecainidePropafenoneTocainideQuestion 15 of 20 16. The following tetracycline has the potential to cause vestibular toxicityDemeclocyclineDoxycyclineMinocyclineTetracyclineQuestion 16 of 20 17. Randomized clinical trials are done in which phase of drug testingIIIIIIVIQuestion 17 of 20 18. A person consumes large quantities of alcohol daily since 20 years.he is physically dpendent on alcohol.Drug that should not be given to this person isDisulfiramChlordiazepoxideNaltrexoneAcamprosateQuestion 18 of 20 19. Which of the following antibiotic is used in the treatment of clostridium difficile associated diarrheaMetronidazoleClindamycinCiprofloxacinPiperacillinQuestion 19 of 20 20. Design of the study aim to assess the maximum tolerable dose of a new drug is best described asPhase II Randomised control trialPhase I trialPhase III Randomised control trialCase control studyQuestion 20 of 20 Loading...