Pharmacology #6

1. Oral contraceptive (OCP)failure by rifampicin is due to

2. 40 year old patient was taking warfarin 4 gms for DVT prophylaxis. She was given ceftriaxone 8 hrs iv for dental infection. Later the lady experienced episode of vaginal bleeding and darkening of urine. What is the cause?

3. Cyclooxygenase enzyme is not inhibited by

4. A patient without prior medication breathes a gas mixture consisting of 50% N2O and 50% O2 by volume .Which of the following effects would be expected

5. which of the NSAID can be used by parenteral route

6. A drug following first order kinetics is being administered by a constant IV infusion at the rate of 10 mg/min .Its steady-state plasma concentration is 2mg/min. If the dose is increased at 20 mg/dl ,what will be the new steady state plasma concentration

7. 28 yrs old female on oral contraceptives was given tetracycline for treatment of chronic periodontitis by a dentist. After 2 months she became preganant.What is the reason of contraceptive failure?

8. Which drug would treat both dermatophysis and candida infections

9. Cardiac arrythmias are most commonly seen during administration of

10. Which of the following drugs is most likely to be effective against multi-drug resistant strains of M.tuberculosis ,including those resistant to streptomycin

11. Which of the following anti inflammatory drug is a COX 2 inhibitor

12. All of the following are drugs causing SLE or SLE like reaction except

13. All of the following are correct statement except

14. Comparison of efficacy of a new drug B with an existing drug A is done in which phase of clinical trials

15. Angiotensin II causes all except

16. Most common cause of Mobius syndrome is use of which of the following drug in pregnancy

17. Therapeutic drug monitoring is required in all except

18. Drug of choice of malignant hyperthermia

19. Which of the following antimalarial is not a 4-aminoquinoline

20. Which of the following agent causes interstitial nephritis