1. 1 ml of a 10% solution of a drug (weight by vol), contains what amount of drug: 10mg 100mg 1 mg 10 gm 2. Which of the following agent causes interstitial nephritis Amoxicillin Ampicillin Cloxacillin Methicillin 3. when broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may be Reduced because of increased protein binding Increased because of reduction of vitamin K sources Reduced because of enhanced hepatic drug metabolism Increased because of decreased renal excretion of the anticoagulant 4. NSAIDS with least anti-inflammatory action is paracetamol Ketorolac Ibuprofen Indomethacin 5. Hallucinations are seen after following anaesthesia Nitorus oxide Ketamine Thiopentone Fentanyl 6. Which of the following is not true for lidocaine Most physicians use IV lignocaine only in patients with ventricular arrhythmias Undergoes extensive first pass metabolism It is the most cardiotoxic sodium channel blockers Inhibits both active and inactive Na channel 7. Clinically significant drug interaction occurs between pyridoxime and all of the following drugs except Cyclosporine Isoniazid Hydralazine Levodopa 8. Drug of choice in opioid withdrawal: Naloxone Methadone Naltrexone Codeine 9. Which of the following antibiotic is bactericidal action Chloramphenicol Tetracycline Aminoglycosides Erythromycin 10. Malignant hyperthermia is a rare complication of the use of the following anesthetic Ether Halothane Ketamine Thiopentone sodium 11. Which of the following antitubercular drugs is associated with hypothyroidism Streptomycin Pyrazinamide Rifampicin Ethionamide 12. Which of the following drugs is widely used in treating opoid dependent individuals Methadone Alphaprodine Codeine Pentazocine 13. Pulmonary fibrosis is seen with Bleomycin Actinomycin D Cisplatin Methotrexate 14. In pregnancy, all of the following drugs are contraindicated except Proplythiouracil Thalidomide Angiotensin receptor blockers ACE inhibitors 15. 4th generation cephalosporin: Cefixime Cefotaxime Cefepime Cefaclor 16. Side effect of amphotericin B: Renal toxicity Seizures Hepatitis Peripheral edema 17. Post dural (spinal) puncture headache is due to Seepage of CSF Fine needle Toxic effects of drugs Traumatic damage to nerve roots 18. In steady state model of metabolism A->B->C->D, which of the following is true Concentration of B and C is decreased because rate of formation is decreased Concentration of B is increased while that of C is decreased Concentration of B and C is increased Concentration of both B and C is constant because rate of formation is equal to rate of utilisation 19. The plasma half life of aspirin is independent of dose is longer for anti-inflammatory doses compared to that for analgesic dose is shorter for anti-inflammatory doses compared to that for analgesic dose can be increased by alkalinizing the urine 20. Laudanosine is a metabolite of Cis-atracurium Vecuronium Atracurium Pancuronium Loading … Question 1 of 20
