1. In leprosy, the best bactericidal agent is Clofazimine Ethionamide Dapsone Rifampicin 2. Central muscle relaxants act by Blocking conducrion across NM junction Causing CNS depression Inhibiting spinal polysynaptic reflexes Decreasing nerve conduction 3. Most common cause of Mobius syndrome is use of which of the following drug in pregnancy Thalidomide dinoprostone Methotrexate Misoprostol 4. Comparison of efficacy of a new drug B with an existing drug A is done in which phase of clinical trials Phase II Phase III Phase IV Phase I 5. Long-term use of aspirin in rheumatoid arthritis is limited by its propensity to cause Salicylism Hypersensitivity reactions Metabolic acidosis Gastric mucosal damage 6. All are aminoglycosides except kanamycin Netilmycin Azithromycin Streptomycin 7. 1st line systemic antifungal drug for management ofCandidiasis: Fluconazole Miconazole Itraconazole Ketoconazole 8. Desulfuration is an example for Phase 1 decyclization Phase 1 reduction Phase 1 hydrolysis Phase 1 oxidation 9. Which of these is a selective COX-2 inhibitor: Celecoxib lndomethacin Aspirin Ketorolac 10. “shivering” is observed in the early part of postoperative period due to Ether Halothane Trichloroethylene Cholroform 11. The activity of procaine is terminated by Metabolism in the liver and by pseudocholinesterase in the plasma Metabolism in the liver only Elimination by kidney Storage in the adipose tissues 12. Which one of the following skeletal muscle relaxants causes pain on injection Vecuronium Rocuronium pancuronium Succinyl choline 13. Which of the following drugs has spasmolytic activity and could also be used in the management of seizure casued by overdose of a local anaesthetic Diazepam Dantrolene Baclofen Tizanidine 14. Efficacy of a drug refers to Maximum response a drug can produce Affinity of drug to bind the receptors Dose that is required to produce response Affinity of drug that binds to receptors and activates it 15. The infective form of malarial parasite is Hypnozoites Sporozoites Merozoites Trophozoites 16. When comparing opioids with NSAIDS which of the following is correct? Opioids predispose to more bleeding. NSAIDS cause more constipation. NSAIDS cause more drowsiness Opioids impair gastric motility to a greater extent. 17. Which of the following can be safely given in a kidney patient Acetyl salicylic acid Ketorolac Fluconazole Ibuprofen 18. What is true about Tramadol: It is an NSAID Facilitates reuptake of Noradrenaline Causes less respiratory depression than Morphine Increased sensitivity for Mu receptors 19. Which of the following agent causes interstitial nephritis Cloxacillin Amoxicillin Methicillin Ampicillin 20. Extended Multi Drug Resistant Tuberculosis (XDR TB) is classified as resistance to: INH, Rifampicin, all fluoroquinolones and 1 injectable second line drug All 1st and 2nd’ line anti-tubercular drugs INH, Rifampicin and Ethambutol Resistance to !NH, rifampin only Loading … Question 1 of 20
