1. Along with INH which vitamin is given Niacin Cyanocobalamin Riboflavin Pyridoxine 2. Xylometazoline is used before nasal intubation as it causes: Vasoconstriction Relaxation of choanal opening Shrinkage of turbinates Dilation of nasal orifice/increasing chances of bleeding 3. Time dependent killing and prolonged post antibiotic effect is seen with Clindamycin Beta lactam antibiotics Floroquinolones Erythromycin 4. Which of the following statements is not true about NSAIDS Antiplatelet effect of low dose aspirin is related to pre systemic COX inhibition Salicylic acid reduces in vivo synthesis of prostaglandins Acetyl salicylic acid is an irreversible inhibitor of COX enzyme duration of action of aspirin is primarily related to the pharmacokinetic clearance of the drug from the body 5. Angiotensin II causes all except Stimulates aldosterone release Vasodilation Increases thirst Stimulates release of ADH 6. Which of the following agent causes interstitial nephritis Ampicillin Amoxicillin Methicillin Cloxacillin 7. Mechanism of action of chloramphenicol is Glycopeptidase inhibitor cell wall synthesis inhibitor 50s ribosome inhibitor 30 s ribosome inhibitor 8. Misoprostol is a Prostaglandin E1 analogue Antiprogestin Prostaglandin E 2 analogue Prostaglandin antagonist 9. Drug of choice in a patient with renal disorder and Vancomycin resistant MRSA: Erythromycin Daptomycin Teicoplanin Linezolid 10. In pregnancy, all of the following drugs are contraindicated except Proplythiouracil Thalidomide Angiotensin receptor blockers ACE inhibitors 11. Selective COX-2 inhibitor: Nimesulide Aspirin Indomethacin Etoricoxib 12. Second gas effect is exerted by which of the following gas when coadministered with halothane Helium Nitrous oxide Nitrogen Cyclopropane 13. Longest acting sulphonamide Sulfadiazine Sulfamethopyrazine Sulfacetamide Sulfasalazine 14. Fluconazole differs from ketaconazole in that It is more potent inhibitor of drug metabolism It is not active by the oral route It is not effective in cryptococcal meningitis It is unlikely to produce anti- androgenic side effects 15. The therapeutic advantage that penicillin V has over penicillin G is More reliable oral absorption Greater resistance to penicillinase Broader antibacterial spectrum Slower renal excretion 16. True statement regarding development of drug resistance in MRSA is Occurs due to change in penicillin binding proteins Chromosome mediated Treated with amoxicillin + clavulanic acid Results due to penicillinase enzyme production 17. Safest 1st line ATT in renal failure is Ethambutol Isoniazid Rifampicin Streptomycin 18. Mechanism of action of aspirin in MI is Inhibition of Cyclooxygenase Inhibition of thromboxane synthesis Thrombolytic action Decreased serum lipids 19. Central muscle relaxants act by Decreasing nerve conduction Causing CNS depression Blocking conducrion across NM junction Inhibiting spinal polysynaptic reflexes 20. Half-life is directly proportional to All of the above Clearance Plasma concentrations Rate of elimination Loading … Question 1 of 20
