1. Desulfuration is an example for Phase 1 oxidation Phase 1 reduction Phase 1 hydrolysis Phase 1 decyclization 2. Which of the following statement is not true about NSAIDS Many NSAIDS can be used topically NSAIDS are useful in neuropathic pain NSAIDS should be avoided in renal disease as they can cause nephrotoxicity They interfere with the antihypertensives effect of diuretics 3. When comparing opioids with NSAIDS which of the following is correct? Opioids impair gastric motility to a greater extent. Opioids predispose to more bleeding. NSAIDS cause more constipation. NSAIDS cause more drowsiness 4. Penicillin induced hypersensitivity is: Type B Type D Type C Type A 5. A patient suffering from AIDS is on ziduvudine,Lamivudine and indinavir therapy.He develops pulmonary tuberculosis for which treatment is started.Which of the follwing should be avoided in him INH Ethambutol Pyrazinamide Rifampicin 6. Highest therapeutic index: Lithium Penicillin Diuretics Theophylline 7. Therapeutic drug monitoring is required in all except Cyclosporin Tacrolimus Metformin Phenytoin 8. Which of the following penicillin is given by oral route Benzathine penicillin Benzyl penicillin Procaine penicillin Penicillin V 9. Which of the following is a first generation cephalosporin Cefoperazone Cefepime Cefadroxil Cefotaxime 10. A non-competitive inhibitor of an enzyme Decreases Km Increases Km with no or little change in Vmax Decreases Vmax Increases Vmax 11. The antidote of choice in paracetamol poisoning is Methylene blue N-acetylcysteine Flumazenil Sodium bicarbonate 12. Cocaine overdose presents with all of the following except Agitation Constricted pupils Diaphoresis Hypertension 13. Post dural (spinal) puncture headache is due to Seepage of CSF Fine needle Toxic effects of drugs Traumatic damage to nerve roots 14. Mechanism of action of chloramphenicol is 30 s ribosome inhibitor Glycopeptidase inhibitor 50s ribosome inhibitor cell wall synthesis inhibitor 15. Morphine a powerful opioid analgesic drug shuld be avoided in all of the following conditions except Left ventricular failure Pancreatitis Constipation Bronchial asthma 16. All are vasodilators except Lidocaine Chlorprocaine Cocaine Procaine 17. All of the following anticancer agents cause bone marrow depression except Doxarubicin Daunorubicin Chlorambucil Flutamide 18. Which of the following agent causes interstitial nephritis Methicillin Cloxacillin Amoxicillin Ampicillin 19. The infective form of malarial parasite is Merozoites Trophozoites Sporozoites Hypnozoites 20. A patient on aspirin will have increase in Activated partial thromboplastin time Prothrombin time Clotting time Bleeding time Loading … Question 1 of 20