1. Laudanosine is a metabolite of Pancuronium Cis-atracurium Atracurium Vecuronium 2. Which drug would treat both dermatophysis and candida infections Ketoconazole Nystatin Griseofulvin Tolnaftate 3. One of the following is not an antifungal agent Clofazimine Ciplopirox Ketoconazole Undecyclenic acid 4. All are antiplatelet drugs except Dipyridamole Aspirin Clopidogrel Warfarin 5. Which of the following antimalarial is not a 4-aminoquinoline Primaquine Chloroquine Mefloquine Amodiaquine 6. “shivering” is observed in the early part of postoperative period due to Ether Halothane Trichloroethylene Cholroform 7. Efavirenz is used for the treatment of HIV infections,It acts As integrase inhibitor As protease inhibitor As reverse transcriptase inhibitor By inhibiting the HIV entry into the cell 8. Mechanism of action of aspirin in MI is Thrombolytic action Inhibition of thromboxane synthesis Decreased serum lipids Inhibition of Cyclooxygenase 9. Elevation of glucose by corticosteroids is counteracted by insulin is an example Competitive antagonism Noncompetitive antagonism Physiological antagonism CHEMICAL antagonism 10. Grapefruit juice is an Enzyme inhibitor Enzyme modulator Enzyme inducer None 11. While prescribing a drug the term ‘HS’ indicates Taken at the time of retiring 1/2 tab daily 1/2 teaspoon daily Once any time 12. The plasma half life of aspirin is shorter for anti-inflammatory doses compared to that for analgesic dose can be increased by alkalinizing the urine is independent of dose is longer for anti-inflammatory doses compared to that for analgesic dose 13. The therapeutic efficacy of antihypertensive drugs is blunted by NSAIDS because they Decrease the synthesis of vascular prostacyclin Cause Sodium excretion Increase the clearance of antihypertensive drugs Decrease the absorption of antihypertensives drugs 14. All of the following are drugs causing SLE or SLE like reaction except Isoniazid Penicillin Hydralazine Sulphonamide 15. Xylometazoline is used before nasal intubation as it causes: Relaxation of choanal opening Shrinkage of turbinates Dilation of nasal orifice/increasing chances of bleeding Vasoconstriction 16. A drug has a half life of 4 hours. If 2 grams of the drug are given every 4 hours, what will be the amount in grams in the body immediately after the third dose 4 3.5 1.5 2 17. True statement regarding development of drug resistance in MRSA is Treated with amoxicillin + clavulanic acid Occurs due to change in penicillin binding proteins Chromosome mediated Results due to penicillinase enzyme production 18. The persistent suppression of bacterial growth that may occur after limited exposure to some antimicrobial drug is called Post antibiotic effect Sequential blockade Concentration dependent killing Time dependent killing 19. Second gas effect is exerted by which of the following gas when coadministered with halothane Nitrous oxide Cyclopropane Nitrogen Helium 20. When 2 drugs A and B are compared false statement is If 1 mg of drug A produces same effect as 3 mg of drug B then A is more potent than B If drug A produces more effect than maximum tolerable dose of drug B then A is more efficacious than B If 1 mg of drug A has higher degree of same effect than 1 mg of drug B then A is more efficacious than B Dose and drug efficacy are not related Loading … Question 1 of 20
