1. When treating hypertension chronically, orthostatic hypertension is maximum withPrazosinPropanololClonidineGuanethidineQuestion 1 of 20 2. Osteomalacia is adverse effect of:carbamazepineValproic acidPhenytoinPrimidoneQuestion 2 of 20 3. 40 year old patient was taking warfarin 4 gms for DVT prophylaxis. She was given ceftriaxone 8 hrs iv for dental infection. Later the lady experienced episode of vaginal bleeding and darkening of urine. What is the cause?ceftriaxone inhibits metabolism of warfarinGut flora was inhibited by ceftriaxoneceftriaxone is an enzyme inducerBoth have additional trombocytopenic effectQuestion 3 of 20 4. Which of the following action is ascribed to Delta type of opiod receptorsReduced intestinal motilityRespiratory depressionEuphoriaSupraspinal analgesiaQuestion 4 of 20 5. Bacteriostatic antitubercular drug isPyrazinamideINHEthambutolRifampinQuestion 5 of 20 6. Noradrenergic and specific serotonergic antidepressants (NaSSAs):DuberoxitineDuloxitineTianeptineMirtazapineQuestion 6 of 20 7. which antidiabetic drug should be stopped before administration of general anaesthesiagilblencamidemetforminpioglitazoneglipizideQuestion 7 of 20 8. Frontal headache is caused by which of the following:lndomethacinMeproxicamAcetaminophenKetorolacQuestion 8 of 20 9. Which of the following statements is not true about NSAIDSduration of action of aspirin is primarily related to the pharmacokinetic clearance of the drug from the bodySalicylic acid reduces in vivo synthesis of prostaglandinsAntiplatelet effect of low dose aspirin is related to pre systemic COX inhibitionAcetyl salicylic acid is an irreversible inhibitor of COX enzymeQuestion 9 of 20 10. In patient of head injuries with rapidly increasing intracranial tension without haematoma, the drug of choice for initial management would beSteroidsLasix20 percent MannitolGlycineQuestion 10 of 20 11. Clindamycin acts by inhibitingProtein synthesisLysosomal enzymesDNA gyraseInhibition of cell wall synthesisQuestion 11 of 20 12. Anaesthetic agent which is explosive in the presence of cauteryEtherTrileneNitorus oxideHalothaneQuestion 12 of 20 13. The activity of procaine is terminated byMetabolism in the liver onlyStorage in the adipose tissuesMetabolism in the liver and by pseudocholinesterase in the plasmaElimination by kidneyQuestion 13 of 20 14. Drug of choice in opioid withdrawal:MethadoneNaloxoneCodeineNaltrexoneQuestion 14 of 20 15. More potent and non toxic drug against herpes virus isZidovudineAmontidineNystatinAcyclovirQuestion 15 of 20 16. Which drug is used in morphine withdrawalFlumazenilMethadoneNaloxonePethidineQuestion 16 of 20 17. Efficacy of a drug refers toDose that is required to produce responseMaximum response a drug can produceAffinity of drug to bind the receptorsAffinity of drug that binds to receptors and activates itQuestion 17 of 20 18. Which of the following antihypertensive drug does not alter seru glucose and lipid levelsThiazide diureticsPropranolPrazosinNone of the aboveQuestion 18 of 20 19. Ibuprofen acts onCyclooxygenase pathwayKinin systemSerotonin systemLipooxygenase pathwayQuestion 19 of 20 20. Which of the following immunosuppresant drug is nephrotoxicCyclophosphamideAzathioprineTacrolimusMycophenolate mofetilQuestion 20 of 20 Loading...
