1. The activity of procaine is terminated byElimination by kidneyStorage in the adipose tissuesMetabolism in the liver and by pseudocholinesterase in the plasmaMetabolism in the liver onlyQuestion 1 of 20 2. Drug used for treatment of ventricular arrhythmiaDiltiazemLidocaineDigitalisDigoxinQuestion 2 of 20 3. Which of the following statement is not true about NSAIDSMany NSAIDS can be used topicallyNSAIDS are useful in neuropathic painNSAIDS should be avoided in renal disease as they can cause nephrotoxicityThey interfere with the antihypertensives effect of diureticsQuestion 3 of 20 4. Release of histamine and leukotrienes from mast cells is prevented byNedocromil sodiumZileutonZafirlukastFexofenadineQuestion 4 of 20 5. Fluconazole differs from ketaconazole in thatIt is not active by the oral routeIt is not effective in cryptococcal meningitisIt is more potent inhibitor of drug metabolismIt is unlikely to produce anti- androgenic side effectsQuestion 5 of 20 6. which of the NSAID can be used by parenteral routeKetorolacFenoprofenNaproxenIbuprofenQuestion 6 of 20 7. In which type of poisonings is gastric lavage contraindicatedsedative drug poisoningorganophosphorus poisoningbarium carbonate poisoningCorrosive acid poisoningQuestion 7 of 20 8. An antihypertensive drug that causes positive Coomb's test isClonidineHydralazineSodium-nitroprussideMethyldopaQuestion 8 of 20 9. All are true of paracetamol poisoning exceptAsymptomatic for 24-30 hoursAcetylcysteine in antidoteAcetylcysteine rejuvenates glutathione stores in paracetamol poisoning10 mg is safe doseQuestion 9 of 20 10. Elevation of glucose by corticosteroids is counteracted by insulin is an exampleNoncompetitive antagonismPhysiological antagonismCHEMICAL antagonismCompetitive antagonismQuestion 10 of 20 11. Alcohol when ingested is eliminated by:First pass metabolismRedistributionEnterohepatic circulationZero order kineticsQuestion 11 of 20 12. Bacteriostatic antitubercular drug isINHPyrazinamideEthambutolRifampinQuestion 12 of 20 13. Efavirenz is used for the treatment of HIV infections,It actsAs reverse transcriptase inhibitorBy inhibiting the HIV entry into the cellAs integrase inhibitorAs protease inhibitorQuestion 13 of 20 14. Which of the following is least nephrotoxicPolymixin BStreptomycinDoxycyclineGentamicinQuestion 14 of 20 15. All are aminoglycosides exceptkanamycinNetilmycinStreptomycinAzithromycinQuestion 15 of 20 16. All of the following statements about opioids is correct exceptPentazocine shows withdrawl symptoms in opioid dependent patientsEthoheptazine is similar to pethidine chemicallyPentazocine and buprenophrine are both complex action opioidsPartial agonists are free from classic opioid aderse effectsQuestion 16 of 20 17. What is NOT true for selective COX-2 inhibitor isThey donot offer the cardio protective effectThe analgesic and anti-inflammtory effects identical to that of non selective NSAIDfewer incidence of gastrointestinal side effectsafe in patients with renal insufficiencyQuestion 17 of 20 18. Randomized clinical trials are done in which phase of drug testingIVIIIIIIQuestion 18 of 20 19. Therapeutic drug index is used to assessEfficacyToxicitySafetyPotencyQuestion 19 of 20 20. Which one of the following agents sensitises the myocardium to catecholaminesIsofuranePropofolHalothaneEthaneQuestion 20 of 20 Loading...
