1. Which of the following anti inflammatory drug is a COX 2 inhibitor Sulindac Aspirin Ketoprofen Rofecoxib 2. Drug of choice for pseudomembranous enterocolitis Linezolid cephalexin Oral vancomycin clindamycin 3. During general anesthesia, all of the following should be monitored EXCEPT blood pressure. pupil diameter. oxygen saturation heart rate. 4. All of the following are correct statement except Leukotrienes causes smooth muscle contraction PGs and leukotrienes are derived from arachidonic acid COX I is an inducible enzyme COX II is induced by cytokines at the site of inflammation 5. Pharmacovigilance means Monitoring drug efficacy Monitoring of unethical trade of drugs Monitoring pharma students Monitoring of drug safety 6. Drug of choice of malignant hyperthermia Diazepam Dantrolene potassium Succinylcholine Dantrolene sodium 7. Cardiac arrythmias are most commonly seen during administration of Thiopental Ether Nitrous oxide Halothane 8. Drug resistance in the mycobacterium tuberculosis to isoniazid is seen due to which of the following: Conjugation Transduction Mutation Transformation 9. Clindamycin acts by inhibiting Inhibition of cell wall synthesis Protein synthesis DNA gyrase Lysosomal enzymes 10. Fluconazole resistant candidiasis in a HIV positive patient is treated by Nystatin Ketoconazole Clotrimazole Amphotericin B 11. In steady state model of metabolism A->B->C->D, which of the following is true Concentration of B and C is decreased because rate of formation is decreased Concentration of both B and C is constant because rate of formation is equal to rate of utilisation Concentration of B and C is increased Concentration of B is increased while that of C is decreased 12. 4th generation cephalosporin: Cefaclor Cefixime Cefepime Cefotaxime 13. All of the following anticancer agents cause bone marrow depression except Doxarubicin Chlorambucil Daunorubicin Flutamide 14. Rofecoxib was withdrawn due to liver adenoma Ischemic heart disease Renal complication Gastric ulcer 15. Clinically significant drug interaction occurs between pyridoxime and all of the following drugs except Cyclosporine Isoniazid Levodopa Hydralazine 16. The infective form of malarial parasite is Merozoites Trophozoites Hypnozoites Sporozoites 17. Immediate toxic reactions to local anesthetic administration are most commonly due to excessive blood level of the anesthetic agent. deterioration of the anesthetic agent. hypersensitivity to the vasoconstrictor. hypersensitivity to the anesthetic agent. 18. Which of the following drugs is used to prevent HIV transmission from HIV positive pregnant mother to child Nevirapine Lamivudine Stavudine Didanosine 19. 25 years old asthmatic patient on theophyllline is given ciprofloxacin by dentist. He developed dyspnoea and palpitation. What could be the cause ciprofloxacin inhibits metabolism of theophylline ciprofloxacin reduces plasma protein binding of theophylline ciprofloxacin increases metabolism of theophylline ciprofloxacin displaces receptor binding of theophylline 20. Long acting drug due to enterohepatic circulation: Phenylbutazone Piroxicam Aspirin Sulindac Loading … Question 1 of 20
