1. A patient comes to you complaining that whenever he takes aspirin for headache, he develops severe shortness of breath. Which of t the following may be partly responsible for this Thromboxane A2 Leukotrienes Prostacyclin Prostaglandin E 2. The drug which causes intrinsic staining of teeth due to calcium chelation is Streptomycin Ampicillin Alizarin Tetracycline 3. Which of the following drugs is widely used in treating opoid dependent individuals Codeine Methadone Pentazocine Alphaprodine 4. Use of aspirin in a diabetic patient can result in ketoacidosis Hypoglycemia Hyperglycemia Alkalosis 5. The plasma half life of aspirin is longer for anti-inflammatory doses compared to that for analgesic dose is independent of dose is shorter for anti-inflammatory doses compared to that for analgesic dose can be increased by alkalinizing the urine 6. Which of the following action is ascribed to Delta type of opiod receptors Euphoria Supraspinal analgesia Reduced intestinal motility Respiratory depression 7. which of the NSAID can be used by parenteral route Ketorolac Ibuprofen Fenoprofen Naproxen 8. Which of the following cephalosporins can be used in patients with low GFR Cefixime Cefuroxime Cefoperazone Ceftazidime 9. Which of the following statements is not true regarding sulphonamides Sulphasalazine is absorbed well from GIT Sulphonamides are of value in treatment of infections due to nocardia species Crystalluria can occur with sulphonamide administration Sulphonamide administration to newborn may cause kernicterus 10. Drug resistance in the mycobacterium tuberculosis to isoniazid is seen due to which of the following: Transduction Transformation Mutation Conjugation 11. Buprenorphine is None Pure antagonist Partial agonist Pure agonist 12. Phocomelia is best described as Defect in development of long bones Defect in development of flat bones Defect in cartilage replacement by bones Defect in intramembranous ossification 13. Which can be given safely in renal failure Tetracycline Gentamicin Doxycycline Amphoterecin B 14. Which one of the following agents sensitises the myocardium to catecholamines Ethane Propofol Isofurane Halothane 15. 5HT1 agonists are used as Antipsychotic drug Antianxiety drug For chemotherapy induced vomiting For GERD 16. Drug of choice for pseudomembranous enterocolitis clindamycin Linezolid cephalexin Oral vancomycin 17. What is NOT true for selective COX-2 inhibitor is safe in patients with renal insufficiency fewer incidence of gastrointestinal side effect The analgesic and anti-inflammtory effects identical to that of non selective NSAID They donot offer the cardio protective effect 18. Anti inflammatory dose of aspirin is 1 gm/day 3-6 gm/day 100g/day 150mg/day 19. All of the following statements about opioids is correct except Partial agonists are free from classic opioid aderse effects Pentazocine and buprenophrine are both complex action opioids Ethoheptazine is similar to pethidine chemically Pentazocine shows withdrawl symptoms in opioid dependent patients 20. During general anesthesia, all of the following should be monitored EXCEPT oxygen saturation blood pressure. heart rate. pupil diameter. Loading … Question 1 of 20