1. A distinctive advantage of tetracycline over penicillin is that tetracyclines Are safe to use during pregnancy Have no side effects Have a wider range of antibacteria activity Do not cause super infections 2. Therapeutic drug monitoring is required in all except Tacrolimus Phenytoin Metformin Cyclosporin 3. Amphotericin B is used in treatment of all except Protozoa Fungi Staphylococcus Rickettsiae 4. The persistent suppression of bacterial growth that may occur after limited exposure to some antimicrobial drug is called Concentration dependent killing Time dependent killing Post antibiotic effect Sequential blockade 5. Amphotericin B causes deficiency of Calcium Potassium Sodium Chloride 6. True about aminoglycoside is all except Teratogenic Excreted unchanged in urine Are bacteriostatic Distributed only extracellularly 7. Orange sweat is seen in Pyrazinamide INH Rifampicin Thioacetazone 8. Comparison of efficacy of a new drug B with an existing drug A is done in which phase of clinical trials Phase III Phase IV Phase I Phase II 9. Zero order kinetics occur in following drug with high dose Digoxin and propranolol Alcohol and theophylline Phenytoin and propranolol Amiloride and prebenecid 10. First generation cephalosporin is Cefipime Ceftazidime Cefotaxime Cefadrox 11. Drug of choice of malignant hyperthermia Dantrolene potassium Succinylcholine Diazepam Dantrolene sodium 12. The following causes increased intraocular pressure Thiopentone Ketamine Barbiturate Althesin 13. Elimination after 3 half lives in first order kinetics is 0.75 0.125 0.94 0.875 14. Zero order kinetics is shown by all except High dose salicyclates Phenytoin Methotrexate Ethanol 15. Therapeutic uses of prostaglandin E1 include all of the following except Impotence Primary pulmonary hypertension Maintenance of patent ductus arteriosus Medical termination of pregnancy 16. Erythromycin helps to increase intestinal motility by Action on motilin receptor It increases microbial count in the intestine Action on ADH receptor (adenyl cyclate) It reduces the number of microbes in intestine 17. Long acting drug due to enterohepatic circulation: Phenylbutazone Sulindac Aspirin Piroxicam 18. Dissociative anesthesia is produced by Ketamine Fentanyl Propofol Both (a) and (b) are correct 19. All of the following are drugs causing SLE or SLE like reaction except Sulphonamide Isoniazid Penicillin Hydralazine 20. Which of the following acts by inhibiting cell wall synthesis: Erythromycin Ciprofloxacin Nalidixic acid Penicillin Loading … Question 1 of 20
