1. Component of tubercle bacilli which produces granuloma is Sulfatide Hetero polysaccharide Surface glycolipids Sulfadase 2. Cross beta-pleated sheet structure in amyloidosis is determined by: X-ray crystallography Light microscopy Polarized microscopy Electron microscopy 3. All of the following vascular changes are observed in acute inflammation, except – Decreased hydrostatic pressure. Stasis of blood. Vasodilation. Increased vascular permeability. 4. Which of the following drug is not used for management of acute pulmonary oedema Phenylephrine Dopamine Norepinephrine Dobutamine 5. Nephrotic syndrome causes: Hyperkalaemia Hypokalaemia Hypermagnesemia Hypercalcemia 6. Best test for mycoplasma infection is gram stain of transtracheal aspirate CXR PCR of respiratory secretions Culture of transtracheal aspirate 7. Which of the following coagulation factors causes cross linking and stabilisation of clot Factor VIII factor XIII Thrombin Factor IX 8. Diabetes mellitus affects all except: Heart Brain Lung Kidney 9. Tachycardia, nervousness, intolerance to heat and exophthalmos are seen in Hyperthyroidism Hypoparathyroidism Hyperparathyroidism Hypothyroidism 10. During management of ventricular fibrillation , what is true about use of vasopressin Used with adrenaline Use every 3 minutes First line drug of choice Never used 11. Opacity around colonies of Clostridium perfringens is due to – Cytokinin Desmotase Lecithinase Theta toxin 12. Generalized edema is known as: Hydropericardium Anasarca Hydrothorax Ascites 13. Sunlight has sterilizing effect because: Ozone is present in the environment It has short wavelength It has long wavelength Heat is present 14. Acute infection causes: Leucopenia Neutropenia Monocytosis Leucocytosis 15. life span of RBC is 1 year 3 years 100 days 14 days 16. Chymotrypsinogen is a Carboxypeptidase Zymogen Transaminase Elastase 17. All of the following drugs are used in pituitary adenoma except Letrozol Octreotide Orlistat Bromocryptine 18. Fluid of choice in infant diarrhoea ORS Sugar water Dextrose Salt water 19. all of the following antibacterial proteins are secreted from primary granules except lysozyme bacterial permeability increasing proteins defensins lactoferrin 20. the sigmoid nature of Hb-O2 dissociation curve is because of beta chain has more affinity for alpha chain binding of one O2 molecule increase the affinity for the next O2 molecule alpha chain has more affinity for O2 than beta chain hemoglobin is acidic in nature 21. Which of the following is decreased as a result of hyperventilation? Arterial oxygen content Arterial oxygen tension (PO2) Cerebral blood flow Arterial pH 22. Following is given with iron to increase its absorption Alkalies Citrus fruits Milk Antacids 23. Two particles have same diameter. The one which will pass easily through glomerular membrane has Any of the above Charge has no relation negative charge Positive charge 24. Chemoreceptors are located in which area Medulla Bifurcation of carotid artery All of the above Arch of aorta 25. Most potent stimulator of naive T cells is: Epithelial cells Macrophage Immature dendritic cells Follicular dendritic cells 26. an important non respiratory function of lungs is potassium balace calcium balance anion balance sodium balance 27. A decrease in which of the following parameters would tend to increase the glomerular capillary hydrostatic pressure? Bowman’s capsular hydrostatic pressure Efferent arteriolar resistance Capillary filtration coefficient Afferent arteriolar resistance 28. maximum potassium ions secretion is seen in jejunal secretion saliva gastric secretion colonic secretions 29. Which of the following would shift the oxygen-hemoglobin dissociation curve to the right? Decreased PCO2 Decreased temperature Carbon monoxide poisoning Decreased pH 30. The blood from an 8-year-old boy was analyzed by flow cytometry. The exact number of B cells was counted. Which of the following cell surface markers was likely used to identify the B cells in this blood sample? CD19 CD8 CD4 CD3 31. Treatment of asymptomatic bradycardia is Cardiac pacing No treatment is required Isoprenaline Give atropine 32. Decreased basal metabolic rate is seen in: Feeding Hyperthyrodism Exercise Obesity 33. Actinomycetes is Fungus Gram negative bacteria ram positive bacteria A yeast like form 34. Malignant tumour that shows periosteal reaction: Osteosarcoma Garre’s osteomyelitis Ewing’s sarcoma Osteoclastoma 35. Bile acids consist of all except Deoxycholic add Lithocholic acid Chendeoxycholic acid Taurocholic acid 36. You have to draw blood from a patient. When will you give EDTA? EDTA will be added in test tube Orally starting several days before Through I.V. route before drawing blood EDTA is not an anticoagulant 37. Which of the following is not used as disinfectant for skin preparation due to its irritation potential: Hexachloropropane Alcohol Hexidine Hypochlorite 38. A protoplast is best described as a bacterial cell Containing a cell wall and a capsule Free of cell wall and capsule Uniquely sensitive to penicillin With a cell wall but free of capsule 39. Ocular bobbing is seen in Pontine damage Medulla damage Cerebellum damage mid brain damage 40. Causative organism for gas gangrene Strep. Faecalis Clostridium tetani E. Coli Clostridium welchii 41. Insulin resistant DM: Type II All DM are sensitive to insulin Type I Juvenile onset 42. Which of these is true about antibodies: IgM is seen in secondary response IgM is an acute phase reactant Secretory part of IgA is synthesized by plasma cells IgE mediated delayed hypersensitivity 43. Ulthoff sign is seen in: Cerebral palsy Multiple sclerosis Alzheimer’s disease Parkinsonism 44. Organism most resistant to sterilization: Spores Mycobacteria Prions Fungus 45. nitrogen narcosis is caused due to increase production of nitrous oxide nitrogen inhibits dismutase enzyme increase solubility of nitrogen in nerve cell membrane decrease in oxygen free radicals 46. Potential developed due to movement of freely diffusible ions across a semi permeable membrane is calculated using Nernst equation Fick principle Gibbs equation Goldman-Hodgkin-Katz equation 47. The mechanism by which most fungi cause disease Exotoxin production Hypersensitivity Lecithinase production Coagulase production 48. Which type of necrosis listed below is the basic and most common type? Liquefactive necrosis Gangrenous necrosis Gaseous necrosis Coagulative necrosis 49. Anemia in a newborn can result from: Impaired production of red blood cells Excessive blood loss during delivery All of the above Excessive destruction of red blood cells 50. The oxygen hemoglobin dissociation curve is sigmoid because Oxygen affinity of haemoglobin decreases when the pH of blood falls Binding of one oxygen molecule decrease the affinity of binding other O2 molecules Binding of oxygen to hemoglobin reduces the affinity of Hb for CO2 Binding of one oxygen molecule increases the affinity of binding other O2 molecules 51. Immunoglobulin crossing placenta is IgG IgD IgA IgM 52. Endotoxic shock is initiated by Peripheral vasodilatation injury to endothelial cells failure of myocardial pump inadequate blood voumes 53. Stain used for histologic demonstration of candida hyphae Hematoxylin & Eosin Acridine orange PAS Carbol fuschin 54. Causative organism for native valve infective endocarditis: Staph aureus E. CoIi Hemophilus Gram negative organisms 55. Effusion in TB is characterized by: High glucose Effusion LDH/Serum LDH= < 0.6 Few cells, Protein >3 gm/dL 56. Doppler ultrasound, all are true except? Monophasic tracing measure normal flow Degree of stenosis Provide information about blood velocity Direction of blood flow 57. ST segment of ECG corresponds to Ventricular repolarisation Atrial depolarisation Ventricular depolarization AV conduction 58. Filgrastim is used for treatment of Neutropenia Neutrophenia Polycythemia Anemia 59. A 60 years old patient having cardiorespiratory arrest in hospital ward, for oxygenation what should be done immediately? Tracheostomy Oral intubation Nasal intubation Cricothyroid membrane puncture 60. Which one of the following clinical findings excludes the diagnosis of polymyositis Abdominal muscle involvement Neck muscle involvement Dysphagia Extraocular muscle involvement 61. which of the following is absorbed in stomach salts amino acids alcohols fatty acids 62. Jaundice refers to yellow discoloration of the skin, sclera, and tissues caused by: Hyperbilirubinemia Hypercaicemia Hyperlipidemia Hyperglycemia 63. First released Immunoglobulin after primary immunization IgE IgM IgD IgG 64. Schwannoma of spinal nerve roots is seen in Turcot syndrome Neurofibromatosis 1 Neurofibromatosis 2 Li-Fraumeni syndrome 65. IL-1 helps in: Inhibits the chemotaxis of neutrophils and macrophages Decreases fibroblast and bone resorption activity Stimulation of T-lymphocytes Inhibition of B-lymphocytes 66. Granuloma is characterized by all of the following except: Initiated by a number of infectious and non infectious agents A reaction of acute inflammation Accumulation of modified macrophages A specific type of chronic inflammation 67. christmas disease occurs due to deficiency of factor VIII factor X factor XI factor IX 68. A patient is admitted in casualty with signs of fever, lymphadenopathay etc. Investigations reveal infection by pseudomonas aeruginosa. Drug of choice includes Doxycycline Piperacillin + Tazobactam Cefalexin Ceftriaxone 69. interference with oxygen exchange in lungs is a type of anoxemia anoxic anoxia hypoxic hyoxia histotoxic hypoxia 70. Under normal conditions, the main drive for respiration is the arterial pH acting through central chemoreceptors arterial PCO2 acting through peripheral chemoreceptors arterial pH acting through peripheral chemoreceptors arterial PCO2 acting through central chemoreceptors 71. Hockey stick appearance in echocardiography is a feature of Aortic stenosis Mitral incompetence Aortic regurgitation Mitral stenosis 72. The best way to sterilize an instrument soaked in AIDS virus is: Dip the instrument in glutaraldehyde Clean and autoclave with dry heat Boiling for 1 hour Moist autoclaving 73. Complement binding Immunoglobin via the classical pathway is – IgD & IgE IgG & IgM IgG & IgA IgG & IgD 74. All of the following are potential pathogens of ororpharynx except: Streptococcus pneumonia H. influenzae E.coli N. Meningitides 75. vit K dependent clotting factors are 7,9,10 3,10,12 3,6,8 2,7,9,10 76. All of the following are possible causes of tetany, except: Rickets (Vitamin D deficiency) Hypertension Hyperventilation Hypoparathyroidism 77. Blood pressure is difficult to measure in a patient with Atrial fibrillation Mitral stenosis Complete heart block Aortic stenosis 78. somatomedian mediates decreased rate of glucose uptake by cells deposition of chondroitin sulphate lipolysis gluconeogenesis 79. Cardiovascular effects seen in AIDS are all except Aortic aneurysm CHF Recurrent arterial embolism Pericardial tamponade 80. Tuberculin test screens for Cell mediated immunity Complement function Phagocyte dysfunction Humoral immunity 81. In poorly controlled Type I diabetes, most common infection is: Cryptococcus Mucormycosis Histoplasmosis Rhinosporidiasis 82. NK CELL acts on viruses because Expression of MHC II on cell surface receptor Expression of MHC I on cell surface receptor Non Expression of MHC I on cell surface receptor NON Expression of MHC II on cell surface receptor 83. Psammoma bodies are found in Metastatic calcification Necrosis Apoptosis Dystrophic calcification 84. Which of the following is likely to be decreased in a patient with severe anemia (Hb less than 7 g/dL)? Arterial O2 saturation Arterial O2 content Arterial PO2 Cardiac output 85. Peripheral nerve regenerates at the rate of mm per day 5 1 0.5 2 86. Carbon dioxide is transported in blood by a variety of mechanisms.Which of the following is quantitatively the most important method for transporting CO2? As sodium bicarbonate in serum As CO2 in gas bubbles As CO2 in physical solution As carbaminohemoglobin 87. Which valve is most affected by rheumatic fever Pulmonary valve Tricuspid valve Aortic valve Mitral valve 88. Episodic generalized weakness is related to all except: Hyponatremia Hypophosphatemia Hypocalcemia Hypokalemia 89. Which of the following is a true statement? Calcalour white stains acanthamoeba red grain positive bacteria appear black Gomori- Methanamine silver stains the fungus Pneumocystis jiroveci green Gram negative bacteria appear .red in Gram staining 90. All of the following statements about staphylococcus aureus are true except Most common source of infection is cross infection from infected people bout 30% of general population is healthy nasal carriers Methicillin resistance is chromosomally mediated Epidermolysin and TSS toxin are superantigen 91. Which of the following controls the salivary secretion? Secretin CCK Gastrin Parasympathetic nervous system 92. Each of the following is a risk factor in atherosclerosis EXCEPT one.Which one is this EXCEPTION? Diabetes mellitus Alcoholism Hypertension Heredity 93. Antibiotic sensitivity and resistance of microorganisms is determined by Direct microscopy DNA probe ELISA Culture 94. Multiple drug resistance of bacteria depends on which of the following: Resistance transfer factor (RTF) All of above Colicigenic factor (Col) Fertility factor (F +) 95. Consider two patients with atherosclerosis, one is diabetic and other is non-diabetic. When compare to non-diabetic, diabetic patient has hundred times increased risk of Myocardial infarction Stroke Lower limb ischemia vertebro basilar insufficiency 96. carbon monoxide transfusion in lungs is diffusion limited as diffusion of CO across blood barrier is slow carboxy hemoglobin has high avidity pCO2 rises in blood immediately on exposure base of lung is poorly ventilated 97. Hemophilia A is caused by defect of gene encoding: Factor 13 Factor 8 Factor 9 Factor 5 98. Which of the following procoagulant proteins binds to tissue factor exposed beneath the endothelium of traumatized blood vessels and initiates the clotting cascade? Fibrinogen Factor X Factor V Factor VII 99. Wheel chair sign is seen in Beckers dystrophy Thomson disease Parkinsonism Duchenne muscular dystrophy 100. Iron absorption takes place in which part of intestine Colon jejunum Duodenum Ileum 101. With regards to temperature requirement, most pathogenic bacteria are: Mesophiles Ciyophiles Psychrophiles Thermophites 102. Both intranulear and intracytoplasmic inclusions are present in which of the following viruses HIV Hepatitis B virus Measles virus Pox Virus 103. C ‘wave in JVP is due to Rapid right ventricular filling Atrial filling with tricuspid valves closed Bulging of tricuspid valve into the right atrium Atrial contraction 104. Proximal convoluted tubule have which type of aquaporins Aquaporin 9 Aquaporin 1 Aquaporin 5 Aquaporin 2 105. Not essential for brain death loss of deep tendon reflex loss of brain stem function loss of pupillary reflex Negative apnea test 106. Which of the following anti-diabetic drugs can be used safely in renal failure Metformin Linagliptin Canagliflozin Sitagliptin 107. which of the following enzyme is stable at acidic pH pepsin chymotripsin carboxypeptidase trypsin 108. Percentage of Total body water to total body weight at birth is 90 percentage 80 percentage 60 percentage 50 percentage 109. Kolmer test is a screening test done for Gonorrhea Lymphoma Tuberculosis Syphilis 110. Incorrect about Lafora’s disease Myoclonus Autosomal recessive Treatment with glucocerebrosidase infusions Diagnosis by DNA sequencing 111. All are true about Leptospirosis except: IgM is formed in 5 days Latent period is 10 days Penicillin G is drug of choice Urine and faeces are main mode of transmission 112. in a healthy patient the spaces between the body contain air fibrous connective tissue water loose connective tissue 113. Malignant epithelial cells have an increased number and wider distribution of which of the following receptors Complement Histamine IL-1 Laminin 114. All of the following statements are true regarding reversible cell injury, except – Formation of blebs in the plasma membrane. Formation of amorphous densities in the mitochondrial matrix. Diminished generation of adenosine triphosphate (ATP). Detachment of ribosomes from the granular endoplasmic reticulum. 115. Mid systolic click is classically heard in Hamman-rich syndrome Congenital Mitral stenosis Mitral valve prolapsed Rheumatic aortic regurgitation 116. In body plethysmography,a person is asked to expire against a closed glottis. What will be the change in the pressure in the lung and the box Decrease in lung, increase in box Decrease in both Increase in lung, decrease in box Increase in both 117. An increase in the size of an organ or tissue due to an increase in the size of cells is known as: Hyperplasia Hypertrophy Aplasia Atrophy 118. Anaphylotoxins: All of the above Produce inflammation Induce smooth muscle contraction Cause enhanced capillary permeability 119. H. pylori infection is seen in all except: Gastric lymphoma Gastric carcinoma Duodenal ulcer Fundal gastritis 120. Characteristic feature of retiovirus is: DNA polymerase Restriction endonuclease Ribonuclease Reverse transcriptase 121. Nitrogen washout method is used for estimating Tidal volume Dead space volume Functional residual capacity Diffusion capacity 122. Regarding leptospirosis all are true except: It is a zoonosis Humans are accidental hosts of the disease Humans are the end hosts Lice act as reservoirs of disease 123. The most appropriate drug use for chelation therapy in beta thalassaemia major is Oral deferiprone oral desferrioxamine Oral succimer Intramuscular EDTA 124. The exact part of the antigen that reacts with the immune system is called as Idiotope Epitope Clone Paratope 125. Sulfonylureas acts by: Increasing cell sensitivity Ca+2 channel activation K+ channel closure Activating DPP-4 126. Kidney stones (renal calculi) are a common complication in a patient with which disorder listed below? Hyperthyroidism Diabetes mellitus Hypopituitarism Hyperparathyroidism 127. Acute infection causes: Leucopenia Leucocytosis Neutropenia Monocytosis 128. Nucleus in reticulocyte is: Absent Fragmented Compact Pyknotic 129. maximum phosphate is reabsorbed in PCT Collecting duct DCT Loop of henle 130. during diastole the arterial pressure is maintained by musculature of arteries elastic recoil of aorta contraction of left ventricle constriction of capillaries 131. why fetal cells continue to divide but terminally differentiated adult cells do not divide phosphatase is absent in fetal cells there are many cyclin inhibitors which prevent cell from entering into S phase in adults proteinase is absent in fetus absence of CD kinase 132. Decreased basal metabolic rate is seen in: Hyperthyrodism Feeding Exercise Obesity 133. Which of the following is not seen in secondary adrenal insufficiency Postural hypertension Hypoglycemia Lassitude Pigmentation 134. which of the following is not a primary taste sour chilli bitter sweet 135. maximum water reabsorption in the GIT occurs in jejunum colon ileum stomach 136. In which of the following disease maternal antibodies are not protective to the child measles Pertusis Chicken pox Rubella 137. decreased basal metabolic rate is seen in exercise obesity feeding hyperthyroidism 138. The following is true about malaria LDH card test quantitates the falciparum parasitaemia Plasmodium falciparum can cause relapse Plasmodium vivax can be detected by HRP-2 dipstick Plasmodium vivax causes enlargement of affected RBC 139. APGAR score is a quantitative method of assessing score of new born status based on Neurologic,digestive and respiratory Neurologic,renal and respiratory Neurologic ,circulatory and respiratory Neurologic,circulatory and renal 140. A patient in emergency with symptoms of tachycardia bronchodilation increased temperature and constipation .He may be suffering from poisoning with Penicillamine Organophosphorus Mushroom Atropine 141. normal pH of stomach is 8 to 9 7 to 7.2 4 to 5 11 to 12 142. basal metabolic rate depends most closely on lean body mass body mass index obesity body surface area 143. normal anion gap is (in mEq/l) 10 to 12 18 to 20 25 to 30 3 to 5 144. Role of bile salts Formation of lipid bilayer Emulsification of lipids Fatty acid degradation Vit B12 absorption 145. Immunoglobin, which is produced first by the fetus in response to Infection IgA IgG IgD IgM 146. Cerebral perfusion pressure is Arterial pressure minus intracranial pressure Arterial pressure minus peripheral venous pressure Venous pressure minus arterial pressure Arterial pressue x venous pressure 147. Most common cause of nephrotic syndrome in adults: Membrano-proliferative glomerulonephritis Focal segmental glomerulonephritis Diffuse glomerulonephritis Minimal change disease 148. The oxygen-hemoglobin dissociation curve shifts to the left under which of the following circumstances? Increased temperature Carbon monoxide poisoning Increased 2,3-diphosphoglycerate (2,3-DPG) D. Increased PCO2 Decreased pH 149. In a pregnant woman, which of the following vaccines is not indicated Hepatitis B DPT MMR Rabies 150. Which of the following enzyme is required to induce the formation of a plasma clot by pathogenic staphylococci Coagulase Fibrinolystin Lysozymet S-protein 151. Pneumococcus can be differentiated from streptococcus by Type of hemolysis Growth characteristics Gram staining Bile solubility 152. Which of the following bone malignancies is most fatal: Giant cell tumor Pagets disease Multiple myelorna Osteosarcoma 153. Streptococcus mutans can be distinguished from other streptococci by Hemolysis on blood agar Production of extracellular polysaccharides Fermentation of mannitol and sorbitol Optochin sensitivity 154. All of the following are characteristic of an exudate, except: Cell-rich Protein-rich Glucose-poor Low specific gravity 155. All of the following clinical features are associated with enteroviruses Myocarditis Pleurodynia Hemorrhagic fever Herpangina 156. Antigenieity is seen in: Cardiolipin Phospholipids Golgi bodies Nuclear membrane 157. Vagal stimulation of the heart causes decrease in heart rate by Decrease in slope of prepotential Decrease in action potential spike Decrease conduction Increase in repolarisation 158. Blood transfusion associated acute lung injury occurs due to Auto immune disorder Genetic susceptibily HLA mediated Nosocomial infections 159. True about polio Spastic paralysis is seen Increased muscular activity leads to increased paralysis paralytic polio is most common Polio drops given only in less than 3 years 160. Differential leucocyte count is used for diagnosis of: Leukocytosis Anemia Leukopenia Eosinophilia 161. Which stage of plasmodium vivax is infective for mosquito? Trophozoite Sporozoite Ookinete Gametocyte 162. Bone lytic lesions along with increase in B-cells derived from hyperplastic bone marrow are seen in: Thallasemia Plasmacytoma Multiple myeloma Hodgkins lymphoma 163. Most important step in management of acute diarrhea: Give antimotility drugs like loperamide Fluid replacement Antibiotic therapy Give motility reducing agents like bismuth 164. The following hepatitis virus is transmitted by faeco-oral route: except Hepatitis B Virus Hepatitis D Virus Hepatitis E Virus Hepatitis C Virus 165. which of the following is the active form of calcium in circulation albumin bound calcium phosphate bound calcium protein bound calcium ionized calcium 166. Urea breath test used for: Kidney Liver Lung Stomach 167. bile acid pool circulates twice between meals 8 times per day 4 times per meal 10 times per day on fasting 168. Tumor lysis syndrome is characterized by all except: Hypercalcemia Hyperuricemia Hyperphosphatemia Hyperkalemia 169. Purkinje fibres are Modified nerve fibres Fibrous tissue Modified cardiac muscle Modified smooth muscle 170. Extrahepatic cholestasis causes: increase bilirubin in both urine and serum Increased bilirubin in urine Increased urobilinogen in serum Increased urobilinogen in urine 171. Fungus affecting reticular endothelial system Cryptococcus neoformans Histioplasma capsulatum Rhizopus Mucormycosis 172. The following immunoglobulin is not known to fix complement IgG IgM IgA IgE 173. Half-Life of free HIV in plasma is: 24 hours 3 months 12 hours 6 hours 174. First sensation to be lost in leprosy Touch Pain Temperature Pressure 175. Platelet aggregation and vasoconstriction caused by: Leukotriene B4 PGD2 PGI2 Thromboxane A2 176. GFR measurement help in determining Blood volume Heart rate Recovery from shock Stage of kidney disease 177. A child on administration of Penicillin developed fever, rashes, urticaria and swelling. It is due to: Ig E mediated hypersensitivity Immune complex cytotoxicity Ig G mediated hypersensitivity Delayed hypersensivity 178. iron in hemoglobin is in complex form ferric form ferrous form free form 179. Windkessel effect in large arteries perform what function Prevent fluctuation in BP provide peripheral resistance Exchange of respiratory gases Maintain intravascular volume 180. Effector region of immunoglobulin is Constant region of light and heavy chain Variable region of light and heavy chain Variable region of heavy chain Constant region of heavy chain 181. Sterilization cycle uses: 121 degrees Celsius, 15 psi, 15 min 160 degrees Celsius, 20 psi, 15 minutes 170 degrees Celsius, 25 psi, 10 min 180 degrees Celsius, 15 psi, 15 min 182. which of the following is not involved in intrinsic pathway factorXI factor XII factor VII factor IX 183. Gram -ve bacteria stain during gram staining: Blue color Green Red color Colorless 184. In classification of Obstructive sleep apnoea (OSA), a severe case is defined as when the number of episodes of apnoea during sleep exceed 25 / hour 15 / hour >30/ hour 10/ hour 185. The single most important laboratory test for determining the virulence of staphylococci is The catalase test Mannitol fermentation Detection of coagulase Hemolysis of sheep erythrocytes 186. Difference in transudate and exudate is that the former has a: Increased specific gravity High protein Cloudy appearance Low protein 187. prion – true is contains DNA/RNA have long incubation period sensitive to most chemical sterilization evokes strong immunologic reaction 188. A 39-year old female presents with fever. The blood culture from the patient grows gram positive small to medium coccobacilli that are pleomorphic occurring in short chains. Direct wet mount from the culture shows tumbling motility. The most likely organism is Erysipelothrix rhusiopathiae Corynebacterium species Enterococcus species Listeria monocytogenes 189. In a 70 kg adult, the fasting blood sugar level is 180 mg/100m1. This is indicative of Ketosis Hypoglycemia Ketoacidosis Hyperglycemia 190. Continuous murmur is seen in all of the following conditions except Coronary AV fistula PDA Pulmonary AV fistula VSD with aortic regurgitation 191. If a person is having ventricular tachycardia,extra systoles appears in P wave QRS complex R wave T wave 192. Investigation of choice to diagnose epilepsy MRI CT Scan Angiogram EEG 193. Angiotensin II causes all of the following, except Aldosterone secretion Stimulation of thirst Increased ADH secretion Vasodilatation 194. physiolgical response to smoking are all except decreased carboxyhemoglobin decreased HDL increased heart rate and increased catecholemine release increased hematocrit 195. Golf ball inclusion bodies in RBC are seen in pernicious anemia HbH disease Normal reticulocytes G6PD deficiency 196. regarding transport of substances through the cell membrane all are true except facilitated diffusion requires carrier protein facilitated diffusion requires energy glucose is transported via facilitated diffusion active transport is an energy deriven process 197. constitutive component of pulmonary endothelium cells thrombin plasminogen activator lipoprotein lipase factor X 198. Most common cause of Resistant hypertension is Non compliance of patient Renovascular disease Obstructive sleep apnea Pheochromocytoma 199. Cytokines are soluble proteins secreted by which of the following cells? Macrophages Lymphocytes Fibroblasts All of the above 200. Largest reserve of energy in body stored as Muscle glycogen Blood glucose Adipose tissue Liver glycogen 201. If a creatinine clearance of 100 mL/min changes to 50 mL/min over 1 year, assuming that there has been no change in diet, which of the following physiologic changes can be expected? A 2-fold increase in creatinine excretion rate 2-fold decrease in blood urea nitrogen concentration A 2-fold increase in plasma creatinine concentration A 2-fold decrease in creatinine excretion rate 202. Salivary amylase is activated by K+ HCO3 Cl Na+ 203. The most important parameter to monitor Dengue haemorrhagic fever is Haemoglobin Total leucocyte count Haematocrit Platelet count 204. Phage conversion is required for: Diphtheria Tularemia All of the above Gonorrhoea 205. Drug of choice in neonatal seizures Pentobarbital Phenobarbitone Topiramate Phenytoin 206. The host tissue response in acute inflammation is all except Necrotizing Granulomatous Exudative Cytopathic 207. Rapid correction of severe hyperglycemia only by insulin causes: Hyperkalemia Hypokalemia Hyponatremia Hypernatremia 208. Acromegaly is Excessive growth caused by the oversecretion of parathyroid hormone Excessive growth caused by the oversecretion of growth hormone Excessive growth caused by the oversecretion of epinephrine Excessive growth caused by the oversecretion of thyroid hormone 209. Most important factor in transport across a membrane Size of particle Concentration gradient membrane thickness Charge of particle 210. Virchow’s triad consists of all except: Platelet plug Endothelial injury Vascular stasis Hypercoagulability 211. Blood agar is Transport media Differential media Enriched media Simple media 212. Branchial cyst opens most commonly in which area: Behind palatopbaryngeal arch Tonsillar fossa Opposite 3rd molar Opposite 2nd molar 213. Techoic acid is present in Cytoplasm of Gram positive organisms Cell wall of Gram positive organisms Cytoplasm of Gram negative organisms Cell wall of Gram negative organisms 214. A 29 yrs old woman with a pregnancy of 17 week has a 10 years old boy with down syndrome. She does not want another down syndrome kid; best advice to her is blood screening at this point of time will clear the exact picture Ultra sound at this point of time will definitely tell her that next baby will be down syndromic or not Amniotic fluid samples plus chromosomal analysis will definitely tell her that next baby will be down syndromic or not No test is required now as her age is below 35 years 215. which of the following statements is true clearance of a substance is always more than GFR if there is tubular secretion fluid coming from the descending limb of loop of henle is hypotonic if clearance of substance is greater than GFR then tubular secretion must be present descending limb of loop of henle is permeable to solutes 216. The cells which have the capacity to multiply throughout their Life Stable cells Labile cells Permanent cells None of the above 217. Which of the following drugs used for diabetes melitis causes lactic acidosis Metformin Glipizide Phenphormin Pioglitazone 218. all are second messengers ecept DAG guanyl cyclise cAMP IP3 219. Function of myenteric plexus is to regulate Motility All of the above Local blood flow GI secretion 220. Which is not seen in Cushing’ syndrome: Osteoporosis Poor wound healing Hypertension Hypoglycemia 221. intrinsic factor of castle is secreted by which of the following cells in gastric glands enterochromaffin cells chief cells B cells parietal cells 222. During normal diastole, which of the following is most important in preventing over- distension of the ventricles? Adjacent lungs Diaphragm Aortic valve Fibrous pericardium 223. rods and cones differ in all except signal transduction light sensitivity acuity wavelength 224. The mechanism of genetic transfer where a phage serves as a vehicle Is Conjugation Transformation Lysogeny Translation 225. Bacteria used in probiotics is E. Coli All Diphtheria Bifidobacterium 226. mean circulatory filling ressure is difference between systemic and pulmonary arterial pressure diff between central venous pressure and central arterial pressure mean arterial pressure arterial pressure taken at the point when heart stops beating 227. In uncompensated diabetic ketoacidosis pH of blood>7.35 Ratio of pCO2 to HCO3 decreases pCO2 increases HCO3 decreases 228. Hematologic investigations of PT/INR are useful to detect defects in: Only extrinsic pathway Extrinsic and common pathway lntrinsic and common pathway Only intrinsic pathway 229. Not true of obstructive sleep apnea Nocturnal asphyxia Prone to hypertension Alcoholism is a cofactor Spirometry is diagnostic 230. Which of the following is true about streptococcus pneumoniae: Gram -ve diplococcic Gram +ve coccobacilli Extracellular grain -ve diplococcic Gram +ve Lanceolate diplococci 231. A nursing staff while putting IV line to a seriously ill patient of HIV accidentally got a needlestick injury. Which of the following investigation will be most appropriate for her Western blot P24 antigen capture assay Blood culture ELISA test 232. If diameter of a vessel is doubled Blood flow decreases sixteen fold Blood flow decreases four fold Blood flow increases sixteen fold Blood flow increases four fold 233. in a normal person which of the following occurs when he becomes supine from a standing position heart rate increases and settles to a higher level there is an immediate increase in venous return decreased perfusion at the apex of lung cerebral blood flow increases 234. Which of the following is not true about from a transfusion related acute lung injury Supportive care is mainstay of treatment Resolves in 2-3 weeks High mortality rate of 10 percent No role of steroids 235. Most common structure compressed by aneurysm of posterior communicating artery in the circle of Willis hypophysis cerebri optic nerve trochlear nerve oculomotor nerve 236. Which of the following does not occur as the blood passes through systemic capillaries Decreased pH Increased hematocrit Shift of haemoglobin dissociation curve to left increased protein content 237. Which of the following conditions is least likely to present as an eccentric osteolytic lesion? Fibrous cortical defect Aneurismal bone cyst Giant cell tumor Simple bone cyst 238. All of the following infections may be transmitted by dental instruments except Hepatitis E HIV Hepatitis C Hepatitis B 239. All of the following are formed via the cyclooxygenase pathway, except: Prostaglandins Leukotrienes Thromboxanes Prostacyclin 240. Earliest marker of renal damage in a known case of diabetes mellitus is: Increase serum creatinine Glycosuria Microalbuminuria Increase serum urea Loading …
