NEET MDS UNIT Test – Oral medicine, Biochemistry, pharmacology, general medicine #1

1. Phocomelia is best described as

2. Anaesthetic agent which is explosive in the presence of cautery

3. Which of the following is not true about from a transfusion related acute lung injury

4. Fluconazole resistant candidiasis in a HIV positive patient is treated by

5. Which of the following drugs is used to prevent HIV transmission from HIV positive pregnant mother to child

6. granulomatous gingivitis shows histopathology similar to

7. dermatotropic viral diseases are

8. which of the following cyst shows maximum amount of recurrence

9. The protein rich in basic amino acids, which functions in the packaging of DNA in chromosomes, is

10. which of the NSAID can be used by parenteral route

11. Drug given for emergency treatment of angina in a patient with ischemic heart disease

12. which of the following enzymes catalyse the irreversible steps of glycolysis

13. Which one of the following clinical findings excludes the diagnosis of polymyositis

14. Filgrastim is used for treatment of

15. Maximum energy is liberated by hydrolysis of

16. drug of choice for treatment of infection caused by methicillin resistant staphylococcus aureus is

17. What is true about Tramadol:

18. Lactate produced anaerobically is used by

19. Drug of choice for the treatment of peptic ulcer caused due to chronic use of NSAIDs is

20. spreading enzyme produced by some species of streptococcus

21. a person with von Gierke’s disease has ketosis. All are true for ketosis in this patient except

22. Mid systolic click is classically heard in

23. Appearance of red macules with, ‘herald sign’ appearing 7-10 days back, 3-4 cm in diameter, shiny ovoid along with skin lumps with silvery sheen is a characteristic of:

24. Ulthoff sign is seen in:

25. Golf ball inclusion bodies in RBC are seen in

26. Citrate to cis aconitate conversion is inhibited by

27. Loading dose depends upon

28. Urinary protein is detected by

29. Which of the following is a precursor of protoporphyrin

30. The most appropriate drug use for chelation therapy in beta thalassaemia major is

31. Which of the following metabolic pathway in carbohydrate metabolism is required for synthesis of nucleic acid

32. Which of the following antibacterial drug is not used in the treatment of malaria

33. Storage form of free energy in the cell is-

34. True regarding dentigerous cyst is all except

35. APC gene is mutated in

36. Grapefruit juice is an

37. Virchow’s triad consists of all except:

38. Local anaesthetic used as an antiarrhythmic agent is

39. Enzyme common between glycogenesis and glycogenolysis

40. Drug of choice of malignant hyperthermia

41. NADPH is produced by

42. Most important factor for calculating dose of NSAIDS in children

43. Inhibition of glycolysis by oxygen is known as

44. Fluid of choice in infant diarrhoea

45. antinuclear antibody is found in

46. Therapeutic drug monitoring is required in all except

47. Wheel chair sign is seen in

48. Cervical cancer caused by:

49. Hematologic investigations of PT/INR are useful to detect defects in:

50. In prolonged starvation the main energy source of brain is

51. Treatment of asymptomatic bradycardia is

52. Not essential for brain death

53. a condition caused by excess of steroid hormone cortisol in the blood level which is caused by pituitary tumor secreting adrenocorticotropic hormone is

54. When 2 drugs A and B are compared false statement is

55. Negative regulator of BMP is

56. Herpetic koilonychia is herpetic infection of

57. Which of the following is NOT associated with osteogenesis imperfecta?

58. All are caused by amino acid deficiency except

59. Fructose intolerance is to

60. Perioral freckles with risk of breast cancer and intestinal cancer is a feature of:

61. Co-factor for L-amino acid oxidase is

62. Which of the following antibiotic is used in the treatment of clostridium difficile associated diarrhea

63. Co prescription of amoxicillin with clavulanic acid is an example of

64. increased levels of alanine in serum after fasting suggests

65. Glutamine replaced by valine in sickle cell anemia is characterised by

66. which amino acid migrates faster on paper chromatography on methyl cellulose medium

67. Role of molecular change in ETC is-

68. Papillary hyperplasia under a denture is usually due to (an)

69. An enzyme not involved in glycolysis is

70. Major source of ammonia in the kidney is

71. Hockey stick appearance in echocardiography is a feature of

72. Most common cause of Mobius syndrome is use of which of the following drug in pregnancy

73. insulin causes lipogenesis by all except

74. All of the following anticancer agents cause bone marrow depression except

75. In steady state model of metabolism A->B->C->D, which of the following is true

76. Ocular bobbing is seen in

77. The most prominent toxic effects associated with acetaminophen use is

78. Hutchison triad includes all of the following except

79. Cross resistance of isoniazid is seen with

80. Which valve is most affected by rheumatic fever

81. Which of the following is not a phase 1 reaction in drug metabolism

82. Most common cause of nephrotic syndrome in adults:

83. Which is not a monosaccharide

84. Eosinophilic granulomas

85. Decreased basal metabolic rate is seen in:

86. Which of the following is an aldose

87. If a person is having ventricular tachycardia,extra systoles appears in

88. Incorrect about Lafora’s disease

89. A 40 years old lady reported with history of pain in right cheek since the last 2 months. The pain is sharp, lancinating and sudden in onset and brief in duration. The attacks are triggered by chewing foo She is normal in between the attacks. What is the diagnosis:

90. Not a characteristic of white infarct:

91. Citrullinemia is due to deficiency of

92. Proteins are seperated on the basis of charge in

93. In oxidative phosphorylation, the ATP production and respiratory chain are linked by-

94. Which of the HPV cause malignancy:

95. The following is true about malaria

96. Edman’s reagent is

97. A child reports with greenish stains on teeth .The most probable cause is

98. Which of the following bone malignancies is most fatal:

99. Sialologue is an agent used to

100. which one of the following shows dense collagenous stroma with compressive thin strands and cords of epithelium cells

101. Tongue shows loss of normal exfoliation of surface epithelium with hypertrophy of filiform papillae in:

102. Which of the following acts by inhibiting cell wall synthesis:

103. Glucose 6 phosphatase deficicency is seen in

104. A 10 year old has diffuse bilateral white areas on the buccal mucosa, dorsum of the tongue and the floor of the mouth. The mother tells the dentist that she has noticed this appearance for at least 3 years, but she was not concerned since she has had a similar condition all of her life. The most likely diagnosis is

105. Patient is suffering from atherosclerosis. Which of the following is the most beneficial drug for prevention of stroke in this patient

106. Key enzyme in glycogenolysis

107. which of the following is the major contributor to colloid osmotic pressure

108. Bacteriostatic antitubercular drug is

109. during phagocytosis the metabolic process called respiratory burst involves the activation of

110. the 40nm gap in between the tropocollagen molecule in collagen which serve as the site of bone formation is occupied by which of the following

111. Which of the following drug inhibits cell wall synthesis

112. What is NOT true for selective COX-2 inhibitor is

113. Amcloblastoma originates from:

114. Which of these is used as a marker of proliferation ( dysplastic proliferation) in a premalignant lesion:

115. which of the following is present in plasma but absent in serum

116. Blood pressure is difficult to measure in a patient with

117. In citric acid cycle,NADH is produced by

118. A post operative patient developed septicaemia and was incorrectly started on combination chemotherapy by a new resident doctor. However, when the patient did not respond even after 10 days of antibiotics treatment, the review of the charts was done. It was found that the resident doctor had started the combination of antibiotics which was mutually antagonistic in action. Which one of the following is the most likely combination that was given

119. First sensation to be lost in leprosy

120. all the statements regarding LDL receptors are true except

121. Which of the following agent causes interstitial nephritis

122. Which of the following is true about hypophosphatasia

123. Tetracycline acts by inhibiting protein synthesis at:

124. Herpes zoster is caused by

125. Schwannoma of spinal nerve roots is seen in

126. Which of the following is not seen in secondary adrenal insufficiency

127. A nursing staff while putting IV line to a seriously ill patient of HIV accidentally got a needlestick injury. Which of the following investigation will be most appropriate for her

128. Which of these is not a cofactor for glycogen phophorylase, an important enzyme of the glycogenolysis pathway

129. “shivering” is observed in the early part of postoperative period due to

130. Which anti tubercular causes reversible Red Orange Urine:

131. Activity of which of the following enzyme is not affected by insulin

132. Multiple supernumerary teeth are most commonly found in

133. Earliest marker of renal damage in a known case of diabetes mellitus is:

134. Cardiovascular effects seen in AIDS are all except

135. During management of ventricular fibrillation , what is true about use of vasopressin

136. A patient is admitted in casualty with signs of fever, lymphadenopathay etc. Investigations reveal infection by pseudomonas aeruginosa. Drug of choice includes

137. Which of the following is not an intermediate of citric acid cycle

138. Involucrum is

139. A 29 yrs old woman with a pregnancy of 17 week has a 10 years old boy with down syndrome. She does not want another down syndrome kid; best advice to her is

140. Acute infection causes:

141. Psammoma bodies are found in

142. Consider two patients with atherosclerosis, one is diabetic and other is non-diabetic. When compare to non-diabetic, diabetic patient has hundred times increased risk of

143. Which amino acid is not involved in transamination

144. Substrate for ATP synthase is-

145. All of the following are sources of acetyl Co-A for fatty acid synthesis except one.Which one is the exception

146. Syndrome associated with predisposition to development of oral cancer is termed as

147. An odour of acetone on the breath can be found in patients with

148. Glycogen breakdown leads to formation of

149. The therapeutic efficacy of antihypertensive drugs is blunted by NSAIDS because they

150. Glucose transporters present in the beta cells of the Islet of Langerhans is

151. Along with INH which vitamin is given

152. collagen is rich in

153. Hairy tongue is associated with hypertrophy of:

154. The conversion of an optically pure isomer (enantiomer) into a mixture of equal amounts of both dextro and levo forms is called as

155. Which one of the following intravenous induction agents is the most suitable for day care surgery

156. Which of the following is th metabolic pathway in which there is a shuttling of glucose and lactate between muscle and liver during physical exercise

157. Amide group is present in which part of protein

158. In uncompensated diabetic ketoacidosis

159. A patient with severely displaced teeth,fractured enamel ,undefined DEJ and severe attrition may be suffering from

160. Blood transfusion associated acute lung injury occurs due to

161. A immunocompromised patient came to your clinic with complain of decreased salivary secretion and foul odor from mouth. On histopathological examination ,Acinar necrosis and squamous metaplasia of salivary duct where observed . what is the diagnosis

162. Endotoxic shock is initiated by

163. All of the following statements about opioids is correct except

164. calcification of falx cerebri is seen in

165. antigen associated with cicatricial Pemphigoid

166. Xylometazoline is used before nasal intubation as it causes:

167. Use of aspirin in children with viral disease is associated with

168. Which of the following drug is not used for management of acute pulmonary oedema

169. Time dependent killing and prolonged post antibiotic effect is seen with

170. Creatinine is formed from

171. GNAS1 Gene mutation is associated with

172. The characteristic feature seen during the histogic examination of a langerhans cell histiocytosis lesion is

173. Natal and neonatal teeth are not associated with

174. A patient in emergency with symptoms of tachycardia bronchodilation increased temperature and constipation .He may be suffering from poisoning with

175. One of the following is not penicillinase susceptible

176. Which of the following anti-diabetic drugs can be used safely in renal failure

177. Which can be given safely in renal failure

178. In leprosy, the best bactericidal agent is

179. In a pregnant woman, which of the following vaccines is not indicated

180. Continuous murmur is seen in all of the following conditions except

181. Which of these is most effective for gluconeogenesis

182. A 60 years old patient having cardiorespiratory arrest in hospital ward, for oxygenation what should be done immediately?

183. The following is not a carrier protein

184. Branchial cyst opens most commonly in which area:

185. which of the following reactions does not convert hydrophobic into hydrophilic groups

186. Fissured tongue is seen in:

187. Least energy producing cycle

188. APGAR score is a quantitative method of assessing score of new born status based on

189. which one of the following does the bisphosphonates primary cause

190. a female patient showing progressive muscle and fat loss on the right side of the face is suffering from

191. 20% KOH used in the diagnosis of candida albicans. Its mechanism of action is

192. The molecule, which is the initiator of cataract formation in the eye lens and whose 1-phosphate derivative is responsible for liver failure is

193. Rofecoxib was withdrawn due to

194. The most important parameter to monitor Dengue haemorrhagic fever is

195. Streptococci adhere to the oral suraces and contribute to caries development as they

196. Ground glass appearance, Brown tumors and hypercalcemia are seen

197. Investigation of choice to diagnose epilepsy

198. 25 years old asthmatic patient on theophyllline is given ciprofloxacin by dentist. He developed dyspnoea and palpitation. What could be the cause

199. Therapeutic index is a measure of

200. Both ketogenic and glucogenic amino acid is

201. Drug of choice in a patient with renal disorder and Vancomycin resistant MRSA:

202. Most common structure compressed by aneurysm of posterior communicating artery in the circle of Willis

203. rheumatoid arthritis, SLE, thyroiditis are examples of

204. A positive Nikolsky’s sign is a diagnostic feature of

205. Regulating enzymes in gluconeogenesis are all ,except

206. Doppler ultrasound, all are true except?

207. Not true of obstructive sleep apnea

208. Folding of protein chain is due to

209. cell differentiation by surface markers

210. A lady complaints her 9 year old daughter is suffering from oral ulceration, fever and shedding of skin from Palm and soles. She also provided history of premature exfoliation of teeth and increased sweating. She also gave history of using new teething gel available in market for past one month. Her daughter is most probably suffering from

211. Drug resistance in Staphylococcus aureus is most commonly acquired by

212. What drug competes with bilirubin to bind with albumin:

213. burning tongue will not be associated with which of the following

214. which one of the following shows ‘blueberry lips’

215. Drug of choice in opioid withdrawal:

216. Glycine is used for synthesis of the following except

217. In which of the following disease maternal antibodies are not protective to the child

218. Which of the following drugs used for diabetes melitis causes lactic acidosis

219. Reducing equivalents produced in glycolysis are transported from cytosol to mitochondria by

220. GLUT-5 is transporter for

221. different sequence of amino acids having similar structure of proteins is an example of

222. Which of the following techniques can be used for exact localisation of a genetic locus

223. Drug of choice in neonatal seizures

224. Mechanism of action of chloramphenicol is

225. All of the following drugs are used in pituitary adenoma except

226. Miescher syndrome is associated with

227. 5HT1 agonists are used as

228. Urea is produced by the enzyme

229. The ground substance of the extracellular matrix is made up of

230. Cyclooxygenase enzyme is not inhibited by

231. Best test for mycoplasma infection is

232. All are vasodilators except

233. Albumin and globulin are classified as

234. Mutation in which chromosome is related to dentinogenesis imperfect

235. A syphilitic gumma is most commonly found on the

236. Citrate synthesase is inhibited by

237. nephrometry is based on the principle of

238. True about polio

239. Most common intraoral infection in diabetic patient:

240. Most common cause of Resistant hypertension is