NEET MDS UNIT Test – Oral medicine, Biochemistry, pharmacology, general medicine #1

1. Citrate to cis aconitate conversion is inhibited by

2. Glutamine replaced by valine in sickle cell anemia is characterised by

3. which one of the following does the bisphosphonates primary cause

4. Phocomelia is best described as

5. Co prescription of amoxicillin with clavulanic acid is an example of

6. Creatinine is formed from

7. which of the following enzymes catalyse the irreversible steps of glycolysis

8. Most common structure compressed by aneurysm of posterior communicating artery in the circle of Willis

9. calcification of falx cerebri is seen in

10. the 40nm gap in between the tropocollagen molecule in collagen which serve as the site of bone formation is occupied by which of the following

11. Virchow’s triad consists of all except:

12. Continuous murmur is seen in all of the following conditions except

13. In steady state model of metabolism A->B->C->D, which of the following is true

14. Tetracycline acts by inhibiting protein synthesis at:

15. What is true about Tramadol:

16. Mid systolic click is classically heard in

17. Drug of choice in opioid withdrawal:

18. Along with INH which vitamin is given

19. All of the following anticancer agents cause bone marrow depression except

20. Eosinophilic granulomas

21. Citrullinemia is due to deficiency of

22. Investigation of choice to diagnose epilepsy

23. Loading dose depends upon

24. Which is the most common manifestation of recurrent HSV1 infection

25. Ulthoff sign is seen in:

26. Urea is produced by the enzyme

27. a person with von Gierke’s disease has ketosis. All are true for ketosis in this patient except

28. Which of the following metabolic pathway in carbohydrate metabolism is required for synthesis of nucleic acid

29. which of the NSAID can be used by parenteral route

30. TSH, LH, FSH act by

31. Reducing equivalents produced in glycolysis are transported from cytosol to mitochondria by

32. which of the following is the major contributor to colloid osmotic pressure

33. cell differentiation by surface markers

34. Major source of ammonia in the kidney is

35. Safest 1st line ATT in renal failure is

36. during phagocytosis the metabolic process called respiratory burst involves the activation of

37. Endotoxic shock is initiated by

38. Inhibition of glycolysis by oxygen is known as

39. Which of the following agent causes interstitial nephritis

40. Which of the following is an aldose

41. Which of the following is not seen in secondary adrenal insufficiency

42. Not true of obstructive sleep apnea

43. The ground substance of the extracellular matrix is made up of

44. Both ketogenic and glucogenic amino acid is

45. In a pregnant woman, which of the following vaccines is not indicated

46. In which type of glycogen storage disease is hyperuricemia a feature

47. GLUT-5 is transporter for

48. APGAR score is a quantitative method of assessing score of new born status based on

49. What is NOT true for selective COX-2 inhibitor is

50. Least energy producing cycle

51. Which of the following is true about hypophosphatasia

52. different sequence of amino acids having similar structure of proteins is an example of

53. A immunocompromised patient came to your clinic with complain of decreased salivary secretion and foul odor from mouth. On histopathological examination ,Acinar necrosis and squamous metaplasia of salivary duct where observed . what is the diagnosis

54. Herpes zoster is caused by

55. Fructose intolerance is to

56. Patient is suffering from atherosclerosis. Which of the following is the most beneficial drug for prevention of stroke in this patient

57. Papillary hyperplasia under a denture is usually due to (an)

58. Edman’s reagent is

59. Which of the following antibacterial drug is not used in the treatment of malaria

60. antigen associated with cicatricial Pemphigoid

61. Involucrum is

62. Schwannoma of spinal nerve roots is seen in

63. Wheel chair sign is seen in

64. Tongue shows loss of normal exfoliation of surface epithelium with hypertrophy of filiform papillae in:

65. Filgrastim is used for treatment of

66. Highest therapeutic index:

67. Which of the HPV cause malignancy:

68. A lady complaints her 9 year old daughter is suffering from oral ulceration, fever and shedding of skin from Palm and soles. She also provided history of premature exfoliation of teeth and increased sweating. She also gave history of using new teething gel available in market for past one month. Her daughter is most probably suffering from

69. The most prominent toxic effects associated with acetaminophen use is

70. gluconeogenesis in fasting state is indicated by

71. Which of these is most effective for gluconeogenesis

72. Use of aspirin in children with viral disease is associated with

73. A 10 year old has diffuse bilateral white areas on the buccal mucosa, dorsum of the tongue and the floor of the mouth. The mother tells the dentist that she has noticed this appearance for at least 3 years, but she was not concerned since she has had a similar condition all of her life. The most likely diagnosis is

74. Which of the following bone malignancies is most fatal:

75. Doppler ultrasound, all are true except?

76. A syphilitic gumma is most commonly found on the

77. A post operative patient developed septicaemia and was incorrectly started on combination chemotherapy by a new resident doctor. However, when the patient did not respond even after 10 days of antibiotics treatment, the review of the charts was done. It was found that the resident doctor had started the combination of antibiotics which was mutually antagonistic in action. Which one of the following is the most likely combination that was given

78. Which one of the following intravenous induction agents is the most suitable for day care surgery

79. collagen is rich in

80. Key enzyme in glycogenolysis

81. The following is not a carrier protein

82. Co-factor for L-amino acid oxidase is

83. Which of the following is not a phase 1 reaction in drug metabolism

84. Which of the following is not true about from a transfusion related acute lung injury

85. A patient is admitted in casualty with signs of fever, lymphadenopathay etc. Investigations reveal infection by pseudomonas aeruginosa. Drug of choice includes

86. Lactate produced anaerobically is used by

87. Enzyme common between glycogenesis and glycogenolysis

88. Negative regulator of BMP is

89. In leprosy, the best bactericidal agent is

90. Therapeutic drug monitoring is required in all except

91. Glycogen breakdown leads to formation of

92. Ocular bobbing is seen in

93. Syndrome associated with predisposition to development of oral cancer is termed as

94. Glycine is used for synthesis of the following except

95. In oxidative phosphorylation, the ATP production and respiratory chain are linked by-

96. Most common cause of Mobius syndrome is use of which of the following drug in pregnancy

97. Natal and neonatal teeth are not associated with

98. A child reports with greenish stains on teeth .The most probable cause is

99. The therapeutic efficacy of antihypertensive drugs is blunted by NSAIDS because they

100. Perioral freckles with risk of breast cancer and intestinal cancer is a feature of:

101. Regulating enzymes in gluconeogenesis are all ,except

102. In citric acid cycle,NADH is produced by

103. Drug resistance in Staphylococcus aureus is most commonly acquired by

104. A patient in emergency with symptoms of tachycardia bronchodilation increased temperature and constipation .He may be suffering from poisoning with

105. a female patient showing progressive muscle and fat loss on the right side of the face is suffering from

106. Ground glass appearance, Brown tumors and hypercalcemia are seen

107. All of the following statements about opioids is correct except

108. True regarding dentigerous cyst is all except

109. NADPH is produced by

110. Maximum energy is liberated by hydrolysis of

111. Substrate for ATP synthase is-

112. A distinctive advantage of tetracycline over penicillin is that tetracyclines

113. Most common intraoral infection in diabetic patient:

114. A 60 years old patient having cardiorespiratory arrest in hospital ward, for oxygenation what should be done immediately?

115. Which of the following antibiotic is used in the treatment of clostridium difficile associated diarrhea

116. which one of the following shows dense collagenous stroma with compressive thin strands and cords of epithelium cells

117. Cardiovascular effects seen in AIDS are all except

118. burning tongue will not be associated with which of the following

119. The following is true about malaria

120. Anaesthetic agent which is explosive in the presence of cautery

121. Which can be given safely in renal failure

122. Psammoma bodies are found in

123. Rofecoxib was withdrawn due to

124. APC gene is mutated in

125. Herpetic koilonychia is herpetic infection of

126. spreading enzyme produced by some species of streptococcus

127. insulin causes lipogenesis by all except

128. Which of these is not a cofactor for glycogen phophorylase, an important enzyme of the glycogenolysis pathway

129. Which of the following drugs is used to prevent HIV transmission from HIV positive pregnant mother to child

130. Golf ball inclusion bodies in RBC are seen in

131. Drug of choice for pseudomembranous enterocolitis

132. which one of the following shows ‘blueberry lips’

133. Hematologic investigations of PT/INR are useful to detect defects in:

134. “shivering” is observed in the early part of postoperative period due to

135. A nursing staff while putting IV line to a seriously ill patient of HIV accidentally got a needlestick injury. Which of the following investigation will be most appropriate for her

136. Grapefruit juice is an

137. Urinary protein is detected by

138. Amcloblastoma originates from:

139. Not a characteristic of white infarct:

140. A 40 years old lady reported with history of pain in right cheek since the last 2 months. The pain is sharp, lancinating and sudden in onset and brief in duration. The attacks are triggered by chewing foo She is normal in between the attacks. What is the diagnosis:

141. Hairy tongue is associated with hypertrophy of:

142. Which anti tubercular causes reversible Red Orange Urine:

143. Storage form of free energy in the cell is-

144. A positive Nikolsky’s sign is a diagnostic feature of

145. Proteins are seperated on the basis of charge in

146. Drug of choice of malignant hyperthermia

147. Hockey stick appearance in echocardiography is a feature of

148. Which of the following anomaly needs consideration in restorative treatment?

149. Cervical cancer caused by:

150. Which one of the following clinical findings excludes the diagnosis of polymyositis

151. All of the following are sources of acetyl Co-A for fatty acid synthesis except one.Which one is the exception

152. 25 years old asthmatic patient on theophyllline is given ciprofloxacin by dentist. He developed dyspnoea and palpitation. What could be the cause

153. Folding of protein chain is due to

154. All are vasodilators except

155. Incorrect about Lafora’s disease

156. Transport of ADP in and ATP out of mitochondria is inhibited by-

157. Which of the following acts by inhibiting cell wall synthesis:

158. A 4-year-old patient comes with her mother for a routine appointment. The mother states that her daughter just started not feeling well and had a mild fever earlier in the day. The daughter has been having trouble swallowing. An intraoral exam reveals multiple 1-mm to 2- mm vesiculopapular lesions of the nasopharynx and soft palate. Your working diagnosis is:

159. Mutation in which chromosome is related to dentinogenesis imperfect

160. Mechanism of action of chloramphenicol is

161. which of the following is present in plasma but absent in serum

162. Which of the following techniques can be used for exact localisation of a genetic locus

163. Treatment of asymptomatic bradycardia is

164. Bacteriostatic antitubercular drug is

165. Activity of which of the following enzyme is not affected by insulin

166. The most appropriate drug use for chelation therapy in beta thalassaemia major is

167. A 29 yrs old woman with a pregnancy of 17 week has a 10 years old boy with down syndrome. She does not want another down syndrome kid; best advice to her is

168. Streptococci adhere to the oral suraces and contribute to caries development as they

169. Not essential for brain death

170. all the statements regarding LDL receptors are true except

171. Consider two patients with atherosclerosis, one is diabetic and other is non-diabetic. When compare to non-diabetic, diabetic patient has hundred times increased risk of

172. Hutchison triad includes all of the following except

173. Role of molecular change in ETC is-

174. One of the following is not penicillinase susceptible

175. The characteristic feature seen during the histogic examination of a langerhans cell histiocytosis lesion is

176. In prolonged starvation the main energy source of brain is

177. Fluid of choice in infant diarrhoea

178. 20% KOH used in the diagnosis of candida albicans. Its mechanism of action is

179. a condition caused by excess of steroid hormone cortisol in the blood level which is caused by pituitary tumor secreting adrenocorticotropic hormone is

180. Which of the following is a precursor of protoporphyrin

181. Time dependent killing and prolonged post antibiotic effect is seen with

182. Most common cause of nephrotic syndrome in adults:

183. Appearance of red macules with, ‘herald sign’ appearing 7-10 days back, 3-4 cm in diameter, shiny ovoid along with skin lumps with silvery sheen is a characteristic of:

184. Blood pressure is difficult to measure in a patient with

185. Acute infection causes:

186. What drug competes with bilirubin to bind with albumin:

187. In uncompensated diabetic ketoacidosis

188. Therapeutic index is a measure of

189. Which of the following is NOT associated with osteogenesis imperfecta?

190. Citrate synthesase is inhibited by

191. Miescher syndrome is associated with

192. increased levels of alanine in serum after fasting suggests

193. All are caused by amino acid deficiency except

194. 5HT1 agonists are used as

195. Decreased basal metabolic rate is seen in:

196. The most important parameter to monitor Dengue haemorrhagic fever is

197. Glucose 6 phosphatase deficicency is seen in

198. During management of ventricular fibrillation , what is true about use of vasopressin

199. Multiple supernumerary teeth are most commonly found in

200. Which is not a monosaccharide

201. which of the following cyst shows maximum amount of recurrence

202. When 2 drugs A and B are compared false statement is

203. All of the following drugs are used in pituitary adenoma except

204. Which valve is most affected by rheumatic fever

205. In which of the following disease maternal antibodies are not protective to the child

206. which amino acid migrates faster on paper chromatography on methyl cellulose medium

207. Most common cause of Resistant hypertension is

208. GNAS1 Gene mutation is associated with

209. Which of the following anti-diabetic drugs can be used safely in renal failure

210. Earliest marker of renal damage in a known case of diabetes mellitus is:

211. Glucose transporters present in the beta cells of the Islet of Langerhans is

212. Best test for mycoplasma infection is

213. nephrometry is based on the principle of

214. You have to draw blood from a patient. When will you give EDTA?

215. Fluconazole resistant candidiasis in a HIV positive patient is treated by

216. Drug of choice for the treatment of peptic ulcer caused due to chronic use of NSAIDs is

217. An enzyme not involved in glycolysis is

218. The molecule, which is the initiator of cataract formation in the eye lens and whose 1-phosphate derivative is responsible for liver failure is

219. The direct immunoflourescence pattern seen in pemphigus vulgaris has been described as

220. granulomatous gingivitis shows histopathology similar to

221. dermatotropic viral diseases are

222. rheumatoid arthritis, SLE, thyroiditis are examples of

223. An odour of acetone on the breath can be found in patients with

224. antinuclear antibody is found in

225. If a person is having ventricular tachycardia,extra systoles appears in

226. True about polio

227. Which of the following drug is not used for management of acute pulmonary oedema

228. Fissured tongue is seen in:

229. Drug of choice in neonatal seizures

230. Which of the following drugs used for diabetes melitis causes lactic acidosis

231. Xylometazoline is used before nasal intubation as it causes:

232. The conversion of an optically pure isomer (enantiomer) into a mixture of equal amounts of both dextro and levo forms is called as

233. Branchial cyst opens most commonly in which area:

234. Drug of choice in a patient with renal disorder and Vancomycin resistant MRSA:

235. Sialologue is an agent used to

236. Most important factor for calculating dose of NSAIDS in children

237. Which of the following drug inhibits cell wall synthesis

238. To differentiate between hemifacial hypertrophy and unilateral fibrous dysplasia of the maxilla evaluation of which of the following would be most useful

239. Which of these is used as a marker of proliferation ( dysplastic proliferation) in a premalignant lesion:

240. A patient with severely displaced teeth,fractured enamel ,undefined DEJ and severe attrition may be suffering from