1. One of the following is a treponemal test for diagnosis of syphilisFTABWidal testWasserman testKahn test 2. Mycotic abscesles are due to:Bacterial InfectionFungal infection.Viral infection.Mixed infection 3. In all of the following bacterial diarrhoeas toxins are implicated as a major pathogenic mechanism exceptVibrio choleraShigellaVibrio parahemolyticusStaphylococcus aureus 4. What is the transport medium for choleraTellurfte MediumCalyblairmediumVenkatramari - Ramaknshrian MediumB&C 5. Process of tissue culture is known as?Macro propagationMicro propagationVegetative propagationChemical propagation 6. Rh incompatibility is which type of hyper sensitivity reaction?Type IType IIType IIIType IV 7. In the management of leprosy, Lepromin test is most useful forDiagnosisPrognosisTreatmentEpidemiological investigations 8. All are true relation to scrub typhus except?Mites act as reservoirTetracycline is the drug of choiceTransmitted when adult mites feed on hostCaused by 0. Tsutsugamushi 9. The genetic ability of a bacterium to grow in the presence of several antibiotics is passed from one bacterium to other byConjugationRarefactionTransductionTransformation 10. Virus mediated transfer of host DNA from one cell to another is known as:Transduction.Transformation.Transcription.Integration. 11. Some bacteria get encapsulated toAchieve protection from phagocytosisTo produce sporesTo increase penetration capacityTo multiply 12. True regarding Malaria:Schizont are infective to mosquitoesTrophozoites are infective to mosquitoesTissue phase is seen in P. FalciparumTissue phase is seen in P. vivax 13. Most antibodies are produced in the:Heart and the liverBrain and the meningesThymus and the appendixSpleen and the Lymph nodes 14. Leprosy bacilli are transmitted from person to person by all except Discharge from nasal mucosaFrom open soreThrough intact skinThrough breast milk 15. Bacteria acquire characteristics by all of the following exceptThrough plasmidsIncorporating part of host DNAThrough bacteriophagesThrough conjugation 16. True about Bacteroides is allSusceptible to most of the antibioticsPresent mainly in mixed infectionThey are bile resistant anaerobesB. fragilis is most virulent 17. All are true about viruses except:Do not show latency between inoculation and diseaseEnveloped virus are more susceptible to environmental conditionsThe nucleic acid is either RNA or DNAAre obligate intracellular parasites 18. With reference to Bacteroides fragilis the following statement are true except?B.Fragilis is the most frequent anaerobe isolated from clinical samplesB.Fragilis is not uniformly sensitive to metronidazoleThe lipo polysaccharide formed by B.Fragilis is structurally and functionally different from the conventional endotoxinShock and DIC are common in Bacteroides bacteremia 19. Staphylococci typically occurs inPairsChainsTetradsIrregular Clusters 20. Leprosy bacilli can be grown inFoot paid on nine branded armadilloTail of guinea pigTestes of albino ratsTestes of guinea pig 21. Positive Shick's test indicates that person isImmune to diphtheriahypersensitive to diphtheriaSusceptible to diphtheriaCarrier of diptheria 22. In penicillin allergy, penicillin acts as a:HaptenCarrierSuper antigenToxin 23. All of the following organisms are known to survive intracellularly except:Neisseria meningitides.Salmonella typhi.Streptococcus pyogenes.Legionella pneumophila. 24. A dark field microscope would.be useful in examining blood forTreponemaActinomycesStreptococcusMycobacterium 25. First organism to appear in oral cavity:Streptococcus sanguisStrept. SalivariousStrept. MutansLactobacilli 26. Acute otitis media in children is most commonly due to:H. InfluenzaM. CatarrhalisSteptococcus pneumoniaStaphylococcus aureus 27. For uniform staining reaction, morphology & biochemical activity, it is advisable to study bacterial cultures during theLag phaseDeath phaseStationary phaseLogarithmic phase 28. Zero growth rate is observed during one of the phases of the bacterial growth curve:LagExponential growthStationary phaseDecline 29. Anaphylaxis refers to theSevere reaction followings the injection of protein solutions in a sensitized individualSevere reaction following primary injection of protein solutionsState of immunity developed by repeated injections of any foreign substanceSevere reaction resulting from sensitivity to common allergens 30. Polypeptide capsule is seen inCorynebacterium diphtheriaClostridium welchiiStaphylococcus aureusBacillus anthracis 31. Post streptococcal acute glomerulus nephritis is an example forType I hypersensitivityType II hypersensitivityType III hypersensitivityType IV hypersensitivity 32. Which organism causes prosthetic valve endocarditis within 60 days of surgeryStreptococcus viridiansStaphylococcus epidermisStaphylococcus aureusFungus 33. Most resistant to antisepticsBacteriaVirusesSporesPrions 34. Commonest site of extra intestinal amoebiasis is:BrainLiverSpleenLungs 35. Bacteria with potent exotoxin islostridium tetaniPseudomonasShigellaKlebsiella 36. Hot air oven is used for sterilization of all EXCEPT:GlasswareRubber tubesSharp instrumentLiquid paraffin 37. Which of the following organisms are arranged in cubical packets of eight cocciStaphylococcusMicrococcusSarcinaAerococcus 38. Moist heat kills all of the following EXCEPT:BrucellaMycobacteriumSalmonellaCoxiella burnetti 39. The property of splitting sugars by bacteria is called:SaprophyticToxogenicSaccharolyticVirulence 40. The medium of choice for growing most fungi isBlood AgarTissue cultureSabourauds agarThioglycollet medium 41. Culture medium for Corynebacterium diphtheriaLoefflers serum slopeMcconkeySaborauds agarLowenstein Jensen Medium 42. Dark ground microscopy is useful to identify:MycoplasmaChlamydiaeRickettsiaeSpirochaetes 43. Group A ?-hemotytic streptococcal infection of the pharynx may be followed in some by:DiphtheriaTyphoid feverRheumatic feverSyphilis 44. All of the following are true regarding chlamydia trachomatis except:It has a bipha'sic lifeInside the cell it evades phagolysosomeReticulate body divides by binary fissionElementary body is metabolically active 45. Adjuvant given along with antigens are going toincrease toxigenicityincrease antigenicityreduce the antigenicityreduce the toxigenicity 46. HIV can be detected and confirmed by:Polymerase Chain Reaction (PCR).Reverse Transcriptase-PCR.Real Time PCR.Mimic PCR. 47. True about Toxaplasma gondi is, it is carried by -CatsDogsRatsCow 48. Which of the following is anaerobic: E.coliBacteroidesPseudomonasKlebsiella 49. Which of the following is not a role of immunoglobulin G (IgG):Crosses placentaHelps in opsonisationProminent in primary immune responseNeutralizes bacterial toxins 50. Which of the following statements related to cross-infection is not true?blood, saliva are regarded as fomites with respect to infection transmissionviral infections are unlikely to spread during the prodromal stageprions are resistant to conventional sterilization methodsDroplet nuclei less than 100 /lm in diameter are entrained in the air for many hours 51. True about meningococci vaccine isCapsule polysaccharide act as a virulent factor for the production of antibodyConjugate vaccine not given in outbreaksPolysaccharide vaccine should be given to children below 2 years of ageVaccine with Polysaccharide B is immunogenic 52. Chlamydia causes all of the following exceptTrachomaMon-gonococcal urethritisPneumoniaParotitis 53. The classic opportunistic infection in acquired immune deficiency syndrome is:Apthous stomatitisTuberculosisPneumocystis carinii pneumoniaHerpetic gingivostomatitis 54. Gram positive cocci which produce greenish colonies when cultured on blood agar, is bile insoluble and does not produce lesions when inoculated intra peritonially in mice, is:Streptococcus mitisStreptococcus pyogenesPneumococciStaphylococci aureus 55. Which of the following structures, found external to the bacterial cell wall, are involved in bacterial attachment to cell surfaces?CapsuleFlagellaPiliMesosomes 56. Resistance of Staphylococcus aureus is due to:PteomorphismElaboration of an enzyme that destroy penicillinPenicillin analogue productionLack of nucleic acid in the cell wall 57. Which of the following is not a feature of anaphylaxis?Delayed reactionImmediate reactionPassive transfer by serumNone of the above 58. Mycobacterium tuberculosis is differentiated from other atypical mycobacteria byNiacin testAFB stainingPAS stainingNone 59. Influenza is caused byOrthomyxo virus, which is a DNA virusParamyxo virus, which is a RNA virusParamyxo virus, which is a DNA virusOrthomyxo virus, which is a RNA virus 60. Signs of typhoid fever is / areHaemorrhagePerforationOsteomyelitisAll of the above 61. Synthesis of antibodies in plasma cells occurs In:Golgi bodyEndoplasmic reticulumNucleusMitochondria 62. Endotoxins have all but one of the properties given below:Produced by gram negative bacteriaProduced by gram positive bacteriaNot secreted outside the cellCannot be toxoided 63. Toxoids areantigenic and toxicantigenic and non-toxicnon-antigenic and toxicnon-antigenic and non-toxic 64. Pleoniorphic' shape of bacteria signifies:Dumb-bell shaped bacteriaIrregular clusters of bacteriaNon specific shapeLong rods shaped bacteria 65. Virus is usually cultured in:Rogosa blood agarSabourouds mediumNon embryonated hen eggsEmbryonated hen eggs 66. Antibody to HSV will begin to appearIn a week and reach a peak in 3 weeksOnly after one yearNo antibodies are present in primary HSVAntibodies are present In recurrent and chronic apthous stomatitis 67. Which of the following is an acid-fast bacillusMycobacterium bacilliTreponema pallidumNeisseria gonorrhoeaALL of the above 68. Immunity that is conferred to the foetus by transfer of IgG and IgA antibodies is called asActive acquired immunityPassive acquired ImmunityNatural active immunityPassive natural immunity 69. EB virus is associated with which carcinoma:Carcinoma of larynxCarcinoma of bladderNasopharyngeal carcinomaChronic lymphocytic leukemia 70. Hemolytic Streptococci can cause serious cross infections in hospital settings. These bacteria usually harbor which site in health workers working in the hospitals:SkinHairNailsThroat 71. The most common pathogens responsible for nosocomial pneumonias in the ICU areGram positive organisms.Gram negative organisms.Mycoplasma.Virus infections. 72. Most of the drug resistance occurs due toTransductionTransformationMutationConjugation 73. Killer and Helper cells are part of:B cellsT cellsMonocytesMacrophage 74. The Ig found in exocrine secretions is:IgGIgDIgMIgA 75. Pentameric structure:IgMIgGIgAIgD 76. Candida albicans causes all of the following exceptEndocarditisMycetomaMeningitisOral thrush 77. A bacterial disease that has been associated with the 3 "Rs" i.e., rats, ricefields, and rainfall isLeptospirosis.Plague.Melioidosis.Rodent-bite fever. 78. Which of the following is an enrichment medium?Blood agarSelenite F BrothMac Conkey agarNutrient Broth 79. Commonest mycobacterial infection in tropical countriesM. LepraeM. Avium intracellulareM. TuberculosisKansasi 80. Delayed tuberculin test response is due toB LymphocytesT lymphocytesMonocytesHistiocytes 81. Which one of the following statement is true regarding pathogenicity of Mycobacteria species?M. tuberculosis is more pathogenic than M. bovis to t he humansM. Kansasii can cause a disease indistinguishable from tuberculosisM. Africanum infection is acquired from the environmental sourceM. Marinum is responsible for tubercular lymphadenopathy 82. Which of the following is true:Hanta virus pulmonary syndrome is caused by inhalation of rodent urine and facesKyanasur forest disease is caused by bite of / wild animalLyssa virus is transmitted by ticksNone 83. Which of the following is true regarding conjugation in bacteria:Sex pili is necessaryTransfer Of double stranded DNA occursLysis of donor bacteriaRequires restriction endonuclease 84. IL-1 and TNF - ? during Inflammation are secreted byPlasma cellsActivated macrophagesLymphocytesPlatelets 85. Which of the following distinguishes viral infections from other microbial Toxin productionProduction of interferonLymphocyte productionNeutrophil production 86. Secretary piece of IgA is synthesized in assaults:T-cellsB-cellsLymph nodesMucosal epithelium 87. Anaerobic bacteria can be cultured inL-J mediumRobertson cooked meat mediumLoefflers mediumSabourauds agar 88. The most common site, where organisms are present in a typhoid carrier is:SpleenGall BladderSalivary glandLiver 89. Exotoxins are:Lipid-polysaccharide complexProtein compoundLipoproteinNone 90. Lance field grouping of streptococci is based on:M proteinCell wall peptidoglycanLipopolysaccharide capsuleCarbohydrate C antigen 91. Phase contrast microscopy is based on principle ofDifferent refractive indices of objectDifferent reflective indices of objectLight scatteringLight attenuation 92. Phase contrast microscopy is based onLight scatterDifferent refractive index BDifferent reflective indexLight attenuation 93. Graft versus host reaction is caused byB-lymphocytesT-lymphocytesMonocytesLeukocytes 94. Nagglers reaction detects-CoagulaseHyaluronidaseLecithinaseNone of the above 95. An advanced diagnostic technique which has been suggested as an alternative to culture methods is:Phase contrast microscopy.Direct immunoflurescence.Latex agglutination.Indirect immunofluorscent microscope assays. 96. Correct order of phases in bacterial growth curve:Log, lag, stationery, declineStationery, log, lag, declineLag, log, stationery, declineDecline, log, lag, stationery 97. Microorganisms of which of the following genera are most predominant in the normal oral floraBacillusStreptococcusLactobacillusStaphylococcus 98. Portion of Immunoglobulin molecule with molecular weight of 50000:Secretary pieceH chainL chainJ piece 99. Sterilization means:Kills all pathogensKills all organisms in a specific environmentKills pathogenic organisms but not sporesKill spores and only pathogenic organisms 100. What is sterilization?Destroying all organism in a given environmentDestroying all organism except sporesKills all pathogenic organismDeactivate the spores and only pathogenic organism Loading...