1. A distinctive advantage of tetracycline over penicillin is that tetracyclinesHave no side effectsHave a wider range of antibacteria activityDo not cause super infectionsAre safe to use during pregnancyQuestion 1 of 20 2. Radio protective drug:CisplatinAmifostineBusulfanDoxorubicinQuestion 2 of 20 3. True statement regarding development of drug resistance in MRSA isOccurs due to change in penicillin binding proteinsTreated with amoxicillin + clavulanic acidChromosome mediatedResults due to penicillinase enzyme productionQuestion 3 of 20 4. Botulinum toxin acts bySecretion of AchMuscle nerve blockInhibits Ach releaseSynthesis of AchQuestion 4 of 20 5. Phase IV clinical trial also called asTherapeutic exploration and dose rangingPost marketing surveillanceTherapeutic confirmationHuman pharmacology and safetyQuestion 5 of 20 6. Use of aspirin in children with viral disease is associated withMetabolic acidosisReye's syndromeRenal tubular acidosisFixed drug eruptionQuestion 6 of 20 7. Not an antimigraine drugPropranololDivalproex sodiumZonisomideFlunarizineQuestion 7 of 20 8. During general anesthesia, all of the following should be monitored EXCEPToxygen saturationpupil diameter.heart rate.blood pressure.Question 8 of 20 9. Toxic effects of long term administration of a glucocorticoid includeLupus like syndromeHepatotoxicityPrecocious pubertyOsteoporosisQuestion 9 of 20 10. The drug of choice in digitalis induced ventricular arrhythmia isPhenytoinQuinidineIV lignocaineProcainamideQuestion 10 of 20 11. All are selective serotonin reuptake inhibitor exceptFluvoxamineParoxetimeAmoxapineFluoxetineQuestion 11 of 20 12. Half-life is directly proportional toRate of eliminationPlasma concentrationsAll of the aboveClearanceQuestion 12 of 20 13. The most prominent toxic effects associated with acetaminophen use isHaemorrhageHepatic necrosisGastric ulcerationRespiratory alkalosisQuestion 13 of 20 14. The most potent and longest acting anaesthetic agent isDibucaineBupivacaineTetracaineLignocaineQuestion 14 of 20 15. In steady state model of metabolism A->B->C->D, which of the following is trueConcentration of both B and C is constant because rate of formation is equal to rate of utilisationConcentration of B is increased while that of C is decreasedConcentration of B and C is decreased because rate of formation is decreasedConcentration of B and C is increasedQuestion 15 of 20 16. The main advantage of giving Glyceryl nitrate by sublingual route isAll of the aboveHas highest lipid solubilityIt avoids toleranceIt bypasses first pass metabolism when given by sublingual routeQuestion 16 of 20 17. Therapeutic drug monitoring is required in all exceptTacrolimusPhenytoinMetforminCyclosporinQuestion 17 of 20 18. when broad spectrum antibiotics are administered with coumarin anticoagulants, the anticoagulant action may beReduced because of increased protein bindingReduced because of enhanced hepatic drug metabolismIncreased because of reduction of vitamin K sourcesIncreased because of decreased renal excretion of the anticoagulantQuestion 18 of 20 19. Tirofiban is aAntianginal drugMonoclonal antibodyAntiplatelet drugAnti-inflammatory drugQuestion 19 of 20 20. All of the following are drugs causing SLE or SLE like reaction exceptSulphonamidePenicillinIsoniazidHydralazineQuestion 20 of 20 Loading...