1. MAO inhibitors patient are contra-indicated in all the following conditions EXCEPTCheeseWith tricyclic antidepressantsWith indirectly acting sympathomimeticAspirinQuestion 1 of 20 2. Major neurotransmitter released at end organ effectors of the sympathetic division of the autonomic nervous system isAdrenalineAcetylcholineNoradrenalineDopamineQuestion 2 of 20 3. A 20 year old female weighing 55 kg is admitted to the emergency department having consumed 10 g of paracetamol together with alohol 6 hours earlier. A serum paracetamol level is reported as 400 micrograms/ml. Which of the following is correct with respect to thisAbnormalities of the kidney function are likely to be presentHepatotoxicity is likely to occurGastric lavage is mandatoryAdministration of activated charcoalQuestion 3 of 20 4. Amphotericin B is used in treatment of all exceptProtozoaFungiStaphylococcusRickettsiaeQuestion 4 of 20 5. When treating hypertension chronically, orthostatic hypertension is maximum withPrazosinClonidineGuanethidinePropanololQuestion 5 of 20 6. Why is nitro glycerine given sublingually:To negate action of vasodilatorFor slow actionFor fast absorption and rapid actionTo take part in first pass effectQuestion 6 of 20 7. A patient suffering from AIDS is on ziduvudine,Lamivudine and indinavir therapy.He develops pulmonary tuberculosis for which treatment is started.Which of the follwing should be avoided in himEthambutolINHPyrazinamideRifampicinQuestion 7 of 20 8. Vasopressor of choice in pregnancy isMephentamineEpinephrineMethoxaminePhenylephrineQuestion 8 of 20 9. Which of the following drugs is most likely to be effective against multi-drug resistant strains of M.tuberculosis ,including those resistant to streptomycinGentamicinAmikacinSpectinomycinClarithromycinQuestion 9 of 20 10. All of the following are true about metformin exceptIncreases Peripheral utilisation of glucose and decreases absorption of glucose from intestineWhen given with alcohol, increases risk of lactic acidosisActs by increased insulin secretionCauses little or no hypoglycaemia in non-diabetic patientsQuestion 10 of 20 11. The plasma half life of aspirincan be increased by alkalinizing the urineis longer for anti-inflammatory doses compared to that for analgesic doseis independent of doseis shorter for anti-inflammatory doses compared to that for analgesic doseQuestion 11 of 20 12. A patient presents to emergency with pinpoint pupil, salivation, lacrimation, tremors, and red tears. Plasma cholinesterase level was 30% of normal. Most probable diagnosis isOpioid poisoningDhatura poisoningPontine hemorrhageOrganophosphate poisoningQuestion 12 of 20 13. Ezetimibe acts byDecreasing absorption of cholesterolEnhancing excretion of bile acidsInhibiting HMG-CoA reductaseInhibiting intracellular lipaseQuestion 13 of 20 14. Drug of choice for anaphylaxisDexamethasonePrednisoloneAminophylineAdrenalineQuestion 14 of 20 15. In which of the following phases of clinical trial of drug ethical clearance is not requiredPhase IIIPhase IIPhase IVPhase IQuestion 15 of 20 16. All of the following drugs are non-selective blockers with no pharmacological action on any other receptor exceptPropanololCarvedilolSotalolTimololQuestion 16 of 20 17. One of the following is not penicillinase susceptiblePenicillin GAmoxicillinPiperacillinCloxacillinQuestion 17 of 20 18. Long term of aluminum hydroxide can causeOsteomalaciaHyperglycemiaVitamin B 12 deficiencyHyperuricaemiaQuestion 18 of 20 19. Drug resistance in Staphylococcus aureus is most commonly acquired byTransformationMutationTransductionConjugationQuestion 19 of 20 20. Which of the following cephalosporins can be used in patients with low GFRCefiximeCefoperazoneCefuroximeCeftazidimeQuestion 20 of 20 Loading...