1. Prolonged administration of streptomycin may result in damage to the Trigeminal nerve Auditory nerve Optic nerve Facial nerve 2. Misoprostol is a Prostaglandin E 2 analogue Prostaglandin E1 analogue Antiprogestin Prostaglandin antagonist 3. Which cephalosporin has anti pseudomonal action Cefaclor Cefoperazone Ceftriaxone Cefotaxime 4. Xylometazoline is used before nasal intubation as it causes: Vasoconstriction Dilation of nasal orifice/increasing chances of bleeding Relaxation of choanal opening Shrinkage of turbinates 5. Grapefruit juice is an Enzyme modulator Enzyme inhibitor Enzyme inducer None 6. Patient is suffering from atherosclerosis. Which of the following is the most beneficial drug for prevention of stroke in this patient Warfarin Digoxin Aspirin Low dose sub cutaneous heparin 7. Ibuprofen acts on Kinin system Cyclooxygenase pathway Lipooxygenase pathway Serotonin system 8. Which of the following drugs is used to prevent HIV transmission from HIV positive pregnant mother to child Lamivudine Didanosine Stavudine Nevirapine 9. 25 years old asthmatic patient on theophyllline is given ciprofloxacin by dentist. He developed dyspnoea and palpitation. What could be the cause ciprofloxacin reduces plasma protein binding of theophylline ciprofloxacin displaces receptor binding of theophylline ciprofloxacin increases metabolism of theophylline ciprofloxacin inhibits metabolism of theophylline 10. Misoprostol,a prostaglandin analogue is useful as Uterine relaxant Anti-ulcer Vasodilator Bronchodilator 11. Which of the following drugs has spasmolytic activity and could also be used in the management of seizure casued by overdose of a local anaesthetic Baclofen Diazepam Tizanidine Dantrolene 12. Drug which can used in management of streptococcal endocarditis susceptible to penicillin, but patient developing immediate allergy following penicillin administration, is Carbenicillin Ceftriaxone Meropenem Vancomycin 13. The most prominent toxic effects associated with acetaminophen use is Hepatic necrosis Respiratory alkalosis Gastric ulceration Haemorrhage 14. Central muscle relaxants act by Inhibiting spinal polysynaptic reflexes Decreasing nerve conduction Blocking conducrion across NM junction Causing CNS depression 15. Which of the following is not a phase 1 reaction in drug metabolism Reduction Hydrolysis Oxidation Conjugation 16. A drug has a half life of 4 hours. If 2 grams of the drug are given every 4 hours, what will be the amount in grams in the body immediately after the third dose 1.5 2 4 3.5 17. The plasma half life of aspirin is independent of dose is longer for anti-inflammatory doses compared to that for analgesic dose is shorter for anti-inflammatory doses compared to that for analgesic dose can be increased by alkalinizing the urine 18. Which of the following intravenous anaesthetic agents is contraindicated in epileptic patients posted for general anaesthesia Ketamine Thiopentone Midazolam Propofol 19. Elevation of glucose by corticosteroids is counteracted by insulin is an example Noncompetitive antagonism Competitive antagonism CHEMICAL antagonism Physiological antagonism 20. A highly ionised drug Is well absorbed from intestine Crosses the placental barrier easily Is highly protein bound Is excreted mainly by kidneys Loading … Question 1 of 20
