1. The following tetracycline has the potential to cause vestibular toxicity Doxycycline Demeclocycline Tetracycline Minocycline 2. When comparing opioids with NSAIDS which of the following is correct? NSAIDS cause more drowsiness NSAIDS cause more constipation. Opioids predispose to more bleeding. Opioids impair gastric motility to a greater extent. 3. Which of the following is a first generation cephalosporin Cefepime Cefotaxime Cefadroxil Cefoperazone 4. Oral contraceptive (OCP)failure by rifampicin is due to Decreased absorption of OCPs Increased metabolism of OCPs Increased binding of OCPs by rifampicin and reduced free drug concentration Increased chances of ovulation due to rifampicin 5. The activity of procaine is terminated by Storage in the adipose tissues Metabolism in the liver and by pseudocholinesterase in the plasma Metabolism in the liver only Elimination by kidney 6. Amphotericin B causes deficiency of Sodium Potassium Calcium Chloride 7. Shortest acting opioid is Fentanyl Remifentanyl Morphine Sufentanyl 8. What is NOT true for selective COX-2 inhibitor is The analgesic and anti-inflammtory effects identical to that of non selective NSAID fewer incidence of gastrointestinal side effect They donot offer the cardio protective effect safe in patients with renal insufficiency 9. In pregnancy, all of the following drugs are contraindicated except Thalidomide Angiotensin receptor blockers Proplythiouracil ACE inhibitors 10. Therapeutic drug monitoring is required in all except Tacrolimus Cyclosporin Phenytoin Metformin 11. Immediate toxic reactions to local anesthetic administration are most commonly due to excessive blood level of the anesthetic agent. hypersensitivity to the anesthetic agent. deterioration of the anesthetic agent. hypersensitivity to the vasoconstrictor. 12. Which of the following cephalosporins can be used in patients with low GFR Ceftazidime Cefuroxime Cefixime Cefoperazone 13. Orange sweat is seen in INH Thioacetazone Pyrazinamide Rifampicin 14. Aminoglycosides cause all of the following except neuromuscular blockade Ototoxicity Nephrotoxicity Cardiotoxicity 15. A non-competitive inhibitor of an enzyme Decreases Km Increases Vmax Increases Km with no or little change in Vmax Decreases Vmax 16. NSAID given in once daily dose is Paracetamol ketorolac Naproxen Piroxicam 17. Which of the following drugs is most likely to be effective against multi-drug resistant strains of M.tuberculosis ,including those resistant to streptomycin Amikacin Gentamicin Spectinomycin Clarithromycin 18. Most common cause of Mobius syndrome is use of which of the following drug in pregnancy Methotrexate dinoprostone Misoprostol Thalidomide 19. Which of the following action is ascribed to Delta type of opiod receptors Respiratory depression Supraspinal analgesia Euphoria Reduced intestinal motility 20. Therapeutic index is a measure of Efficacy Bioavailability potency Drug safety Loading … Question 1 of 20
