1. Anemia in a newborn can result from: Excessive blood loss during delivery Impaired production of red blood cells All of the above Excessive destruction of red blood cells 2. The oxygen hemoglobin dissociation curve is sigmoid because Binding of one oxygen molecule decrease the affinity of binding other O2 molecules Oxygen affinity of haemoglobin decreases when the pH of blood falls Binding of oxygen to hemoglobin reduces the affinity of Hb for CO2 Binding of one oxygen molecule increases the affinity of binding other O2 molecules 3. Both intranulear and intracytoplasmic inclusions are present in which of the following viruses Measles virus Pox Virus HIV Hepatitis B virus 4. Each of the following is a risk factor in atherosclerosis EXCEPT one.Which one is this EXCEPTION? Alcoholism Hypertension Heredity Diabetes mellitus 5. ST segment of ECG corresponds to Ventricular depolarization Atrial depolarisation Ventricular repolarisation AV conduction 6. In classification of Obstructive sleep apnoea (OSA), a severe case is defined as when the number of episodes of apnoea during sleep exceed 25 / hour >30/ hour 15 / hour 10/ hour 7. Immunoglobulin crossing placenta is IgM IgD IgG IgA 8. during diastole the arterial pressure is maintained by contraction of left ventricle elastic recoil of aorta constriction of capillaries musculature of arteries 9. Jaundice refers to yellow discoloration of the skin, sclera, and tissues caused by: Hypercaicemia Hyperbilirubinemia Hyperlipidemia Hyperglycemia 10. False about Staphylococcus lugdunensis Causes infection of native valve Does not produce coagulase Skin commensal Susceptible to antimicrobial 11. The host tissue response in acute inflammation is all except Exudative Granulomatous Cytopathic Necrotizing 12. Immunoglobin, which is produced first by the fetus in response to Infection IgA IgM IgD IgG 13. Differential leucocyte count is used for diagnosis of: Anemia Leukocytosis Leukopenia Eosinophilia 14. Proximal convoluted tubule have which type of aquaporins Aquaporin 2 Aquaporin 9 Aquaporin 5 Aquaporin 1 15. In which of the following disease maternal antibodies are not protective to the child Chicken pox Rubella measles Pertusis 16. Potential developed due to movement of freely diffusible ions across a semi permeable membrane is calculated using Gibbs equation Nernst equation Goldman-Hodgkin-Katz equation Fick principle 17. Which of the following is true about streptococcus pneumoniae: Gram -ve diplococcic Extracellular grain -ve diplococcic Gram +ve Lanceolate diplococci Gram +ve coccobacilli 18. Generalized edema is known as: Hydropericardium Anasarca Hydrothorax Ascites 19. Bacteria used in probiotics is All Diphtheria Bifidobacterium E. Coli 20. Iron absorption takes place in which part of intestine Ileum Colon jejunum Duodenum 21. GFR measurement help in determining Heart rate Blood volume Recovery from shock Stage of kidney disease 22. All are true about Leptospirosis except: IgM is formed in 5 days Penicillin G is drug of choice Latent period is 10 days Urine and faeces are main mode of transmission 23. Which of the following coagulation factors causes cross linking and stabilisation of clot Factor VIII Factor IX Thrombin factor XIII 24. Which of the following is a true statement? grain positive bacteria appear black Calcalour white stains acanthamoeba red Gram negative bacteria appear .red in Gram staining Gomori- Methanamine silver stains the fungus Pneumocystis jiroveci green 25. All of the following are potential pathogens of ororpharynx except: Streptococcus pneumonia E.coli H. influenzae N. Meningitides 26. Organism most resistant to sterilization: Mycobacteria Fungus Spores Prions 27. True about polio Increased muscular activity leads to increased paralysis paralytic polio is most common Polio drops given only in less than 3 years Spastic paralysis is seen 28. somatomedian mediates lipolysis deposition of chondroitin sulphate gluconeogenesis decreased rate of glucose uptake by cells 29. Malignant epithelial cells have an increased number and wider distribution of which of the following receptors Laminin IL-1 Complement Histamine 30. Anaphylotoxins: Induce smooth muscle contraction Produce inflammation Cause enhanced capillary permeability All of the above 31. iron in hemoglobin is in complex form free form ferrous form ferric form 32. NK CELL acts on viruses because Expression of MHC II on cell surface receptor Expression of MHC I on cell surface receptor Non Expression of MHC I on cell surface receptor NON Expression of MHC II on cell surface receptor 33. Causative organism for native valve infective endocarditis: Hemophilus E. CoIi Gram negative organisms Staph aureus 34. which of the following statements is true clearance of a substance is always more than GFR if there is tubular secretion descending limb of loop of henle is permeable to solutes fluid coming from the descending limb of loop of henle is hypotonic if clearance of substance is greater than GFR then tubular secretion must be present 35. Ocular bobbing is seen in mid brain damage Pontine damage Medulla damage Cerebellum damage 36. Platelet aggregation and vasoconstriction caused by: Thromboxane A2 PGI2 Leukotriene B4 PGD2 37. Urea breath test used for: Liver Lung Kidney Stomach 38. Malignant tumour that shows periosteal reaction: Ewing’s sarcoma Osteosarcoma Osteoclastoma Garre’s osteomyelitis 39. In a 70 kg adult, the fasting blood sugar level is 180 mg/100m1. This is indicative of Ketoacidosis Ketosis Hyperglycemia Hypoglycemia 40. Earliest marker of renal damage in a known case of diabetes mellitus is: Increase serum creatinine Increase serum urea Glycosuria Microalbuminuria 41. Which of the following procoagulant proteins binds to tissue factor exposed beneath the endothelium of traumatized blood vessels and initiates the clotting cascade? Factor V Factor X Factor VII Fibrinogen 42. Treatment of asymptomatic bradycardia is Cardiac pacing No treatment is required Isoprenaline Give atropine 43. Endotoxic shock is initiated by injury to endothelial cells failure of myocardial pump Peripheral vasodilatation inadequate blood voumes 44. Blood agar is Simple media Transport media Differential media Enriched media 45. complement factor used to identify activation through common pathway is C5 C4 C3 factor B 46. A nursing staff while putting IV line to a seriously ill patient of HIV accidentally got a needlestick injury. Which of the following investigation will be most appropriate for her ELISA test Blood culture P24 antigen capture assay Western blot 47. Under normal conditions, the main drive for respiration is the arterial pH acting through central chemoreceptors arterial pH acting through peripheral chemoreceptors arterial PCO2 acting through central chemoreceptors arterial PCO2 acting through peripheral chemoreceptors 48. Component of tubercle bacilli which produces granuloma is Sulfatide Hetero polysaccharide Surface glycolipids Sulfadase 49. Which of the following drug is not used for management of acute pulmonary oedema Phenylephrine Norepinephrine Dopamine Dobutamine 50. Which of the following is likely to be decreased in a patient with severe anemia (Hb less than 7 g/dL)? Arterial O2 saturation Arterial PO2 Cardiac output Arterial O2 content 51. Characteristic feature of retiovirus is: Restriction endonuclease Reverse transcriptase DNA polymerase Ribonuclease 52. If a person is having ventricular tachycardia,extra systoles appears in QRS complex T wave R wave P wave 53. During management of ventricular fibrillation , what is true about use of vasopressin Use every 3 minutes First line drug of choice Used with adrenaline Never used 54. Which of the following conditions is least likely to present as an eccentric osteolytic lesion? Simple bone cyst Giant cell tumor Aneurismal bone cyst Fibrous cortical defect 55. C ‘wave in JVP is due to Atrial filling with tricuspid valves closed Rapid right ventricular filling Atrial contraction Bulging of tricuspid valve into the right atrium 56. IL-1 helps in: Decreases fibroblast and bone resorption activity Inhibits the chemotaxis of neutrophils and macrophages Stimulation of T-lymphocytes Inhibition of B-lymphocytes 57. Which stage of plasmodium vivax is infective for mosquito? Trophozoite Gametocyte Ookinete Sporozoite 58. Chemoreceptors are located in which area Bifurcation of carotid artery All of the above Arch of aorta Medulla 59. nitrogen narcosis is caused due to nitrogen inhibits dismutase enzyme increase production of nitrous oxide decrease in oxygen free radicals increase solubility of nitrogen in nerve cell membrane 60. Role of bile salts Formation of lipid bilayer Emulsification of lipids Fatty acid degradation Vit B12 absorption 61. Filgrastim is used for treatment of Neutrophenia Polycythemia Anemia Neutropenia 62. which of the following enzyme is stable at acidic pH pepsin trypsin carboxypeptidase chymotripsin 63. Most important factor in transport across a membrane membrane thickness Charge of particle Concentration gradient Size of particle 64. All of the following are characteristic of an exudate, except: Low specific gravity Glucose-poor Cell-rich Protein-rich 65. Phage conversion is required for: Gonorrhoea All of the above Diphtheria Tularemia 66. Which of the following controls the salivary secretion? Gastrin Parasympathetic nervous system Secretin CCK 67. Chymotrypsinogen is a Elastase Carboxypeptidase Zymogen Transaminase 68. vit K dependent clotting factors are 3,6,8 2,7,9,10 3,10,12 7,9,10 69. In a pregnant woman, which of the following vaccines is not indicated MMR DPT Rabies Hepatitis B 70. intrinsic factor of castle is secreted by which of the following cells in gastric glands parietal cells B cells enterochromaffin cells chief cells 71. Bone lytic lesions along with increase in B-cells derived from hyperplastic bone marrow are seen in: Hodgkins lymphoma Plasmacytoma Multiple myeloma Thallasemia 72. bile acid pool circulates 10 times per day on fasting twice between meals 8 times per day 4 times per meal 73. All of the following vascular changes are observed in acute inflammation, except – Vasodilation. Stasis of blood. Increased vascular permeability. Decreased hydrostatic pressure. 74. Which of the following drugs used for diabetes melitis causes lactic acidosis Glipizide Pioglitazone Phenphormin Metformin 75. Cerebral perfusion pressure is Arterial pressue x venous pressure Arterial pressure minus intracranial pressure Arterial pressure minus peripheral venous pressure Venous pressure minus arterial pressure 76. Carbon dioxide is transported in blood by a variety of mechanisms.Which of the following is quantitatively the most important method for transporting CO2? As sodium bicarbonate in serum As CO2 in gas bubbles As carbaminohemoglobin As CO2 in physical solution 77. Sunlight has sterilizing effect because: It has long wavelength Heat is present Ozone is present in the environment It has short wavelength 78. The following is true about malaria Plasmodium vivax causes enlargement of affected RBC Plasmodium vivax can be detected by HRP-2 dipstick Plasmodium falciparum can cause relapse LDH card test quantitates the falciparum parasitaemia 79. Psammoma bodies are found in Dystrophic calcification Apoptosis Metastatic calcification Necrosis 80. rods and cones differ in all except wavelength light sensitivity acuity signal transduction 81. Which one of the following clinical findings excludes the diagnosis of polymyositis Extraocular muscle involvement Dysphagia Abdominal muscle involvement Neck muscle involvement 82. Most common structure compressed by aneurysm of posterior communicating artery in the circle of Willis optic nerve hypophysis cerebri oculomotor nerve trochlear nerve 83. Branchial cyst opens most commonly in which area: Tonsillar fossa Behind palatopbaryngeal arch Opposite 2nd molar Opposite 3rd molar 84. The most appropriate drug use for chelation therapy in beta thalassaemia major is Intramuscular EDTA Oral succimer Oral deferiprone oral desferrioxamine 85. Decreased basal metabolic rate is seen in: Obesity Hyperthyrodism Feeding Exercise 86. Following is given with iron to increase its absorption Citrus fruits Milk Alkalies Antacids 87. Granuloma is characterized by all of the following except: Initiated by a number of infectious and non infectious agents A specific type of chronic inflammation Accumulation of modified macrophages A reaction of acute inflammation 88. In uncompensated diabetic ketoacidosis Ratio of pCO2 to HCO3 decreases HCO3 decreases pCO2 increases pH of blood>7.35 89. which of the following is the active form of calcium in circulation ionized calcium albumin bound calcium protein bound calcium phosphate bound calcium 90. An increase in the size of an organ or tissue due to an increase in the size of cells is known as: Atrophy Hypertrophy Aplasia Hyperplasia 91. Incorrect about Lafora’s disease Autosomal recessive Myoclonus Treatment with glucocerebrosidase infusions Diagnosis by DNA sequencing 92. basal metabolic rate depends most closely on obesity body surface area body mass index lean body mass 93. Pneumococcus can be differentiated from streptococcus by Growth characteristics Type of hemolysis Bile solubility Gram staining 94. Stain used for histologic demonstration of candida hyphae PAS Carbol fuschin Acridine orange Hematoxylin & Eosin 95. Decreased basal metabolic rate is seen in: Feeding Obesity Exercise Hyperthyrodism 96. carbon monoxide transfusion in lungs is diffusion limited as base of lung is poorly ventilated carboxy hemoglobin has high avidity pCO2 rises in blood immediately on exposure diffusion of CO across blood barrier is slow 97. Which of the following is not seen in secondary adrenal insufficiency Pigmentation Hypoglycemia Lassitude Postural hypertension 98. The blood from an 8-year-old boy was analyzed by flow cytometry. The exact number of B cells was counted. Which of the following cell surface markers was likely used to identify the B cells in this blood sample? CD8 CD4 CD19 CD3 99. Acromegaly is Excessive growth caused by the oversecretion of epinephrine Excessive growth caused by the oversecretion of parathyroid hormone Excessive growth caused by the oversecretion of growth hormone Excessive growth caused by the oversecretion of thyroid hormone 100. Which of the following is not used as disinfectant for skin preparation due to its irritation potential: Alcohol Hexidine Hexachloropropane Hypochlorite 101. The mechanism by which most fungi cause disease Hypersensitivity Exotoxin production Lecithinase production Coagulase production 102. Drug of choice in neonatal seizures Phenobarbitone Phenytoin Topiramate Pentobarbital 103. Tachycardia, nervousness, intolerance to heat and exophthalmos are seen in Hypothyroidism Hypoparathyroidism Hyperparathyroidism Hyperthyroidism 104. Best method of sterilizing disposable syringes: Boiling Hot air oven UV rays Gamma rays 105. Rothera’s test is used to detect: Ketone bodies Carbohydrate Protein Fat 106. Most important step in management of acute diarrhea: Antibiotic therapy Give motility reducing agents like bismuth Fluid replacement Give antimotility drugs like loperamide 107. Function of myenteric plexus is to regulate Local blood flow Motility GI secretion All of the above 108. Kolmer test is a screening test done for Syphilis Tuberculosis Lymphoma Gonorrhea 109. A 39-year old female presents with fever. The blood culture from the patient grows gram positive small to medium coccobacilli that are pleomorphic occurring in short chains. Direct wet mount from the culture shows tumbling motility. The most likely organism is Listeria monocytogenes Corynebacterium species Enterococcus species Erysipelothrix rhusiopathiae 110. Which of the following anti-diabetic drugs can be used safely in renal failure Sitagliptin Canagliflozin Linagliptin Metformin 111. Not essential for brain death loss of brain stem function loss of deep tendon reflex loss of pupillary reflex Negative apnea test 112. Largest reserve of energy in body stored as Adipose tissue Liver glycogen Muscle glycogen Blood glucose 113. Gram -ve bacteria stain during gram staining: Red color Blue color Green Colorless 114. Which of the following is not true about from a transfusion related acute lung injury Resolves in 2-3 weeks No role of steroids Supportive care is mainstay of treatment High mortality rate of 10 percent 115. which of the following is not involved in intrinsic pathway factor XII factor IX factorXI factor VII 116. mean circulatory filling ressure is mean arterial pressure diff between central venous pressure and central arterial pressure arterial pressure taken at the point when heart stops beating difference between systemic and pulmonary arterial pressure 117. Two particles have same diameter. The one which will pass easily through glomerular membrane has Charge has no relation Any of the above Positive charge negative charge 118. Which of the following enzyme is required to induce the formation of a plasma clot by pathogenic staphylococci Fibrinolystin Coagulase Lysozymet S-protein 119. prion – true is sensitive to most chemical sterilization evokes strong immunologic reaction contains DNA/RNA have long incubation period 120. Golf ball inclusion bodies in RBC are seen in HbH disease Normal reticulocytes G6PD deficiency pernicious anemia 121. which of the following is not a primary taste chilli sweet sour bitter 122. all of the following antibacterial proteins are secreted from primary granules except defensins lysozyme lactoferrin bacterial permeability increasing proteins 123. Angiotensin II causes all of the following, except Aldosterone secretion Vasodilatation Increased ADH secretion Stimulation of thirst 124. All of the following are possible causes of tetany, except: Hyperventilation Hypertension Hypoparathyroidism Rickets (Vitamin D deficiency) 125. Which valve is most affected by rheumatic fever Pulmonary valve Aortic valve Mitral valve Tricuspid valve 126. Peripheral nerve regenerates at the rate of mm per day 1 5 0.5 2 127. Effector region of immunoglobulin is Constant region of light and heavy chain Constant region of heavy chain Variable region of heavy chain Variable region of light and heavy chain 128. Streptococcus mutans can be distinguished from other streptococci by Production of extracellular polysaccharides Optochin sensitivity Fermentation of mannitol and sorbitol Hemolysis on blood agar 129. Fluid of choice in infant diarrhoea ORS Salt water Sugar water Dextrose 130. Nephrotic syndrome causes: Hypermagnesemia Hypercalcemia Hyperkalaemia Hypokalaemia 131. Most common cause of nephrotic syndrome in adults: Minimal change disease Membrano-proliferative glomerulonephritis Diffuse glomerulonephritis Focal segmental glomerulonephritis 132. decreased basal metabolic rate is seen in exercise hyperthyroidism feeding obesity 133. In poorly controlled Type I diabetes, most common infection is: Rhinosporidiasis Histoplasmosis Mucormycosis Cryptococcus 134. Which of the following is decreased as a result of hyperventilation? Arterial oxygen content Arterial pH Arterial oxygen tension (PO2) Cerebral blood flow 135. Sterilization cycle uses: 160 degrees Celsius, 20 psi, 15 minutes 121 degrees Celsius, 15 psi, 15 min 170 degrees Celsius, 25 psi, 10 min 180 degrees Celsius, 15 psi, 15 min 136. Cross beta-pleated sheet structure in amyloidosis is determined by: Electron microscopy X-ray crystallography Light microscopy Polarized microscopy 137. Bile acids consist of all except Deoxycholic add Taurocholic acid Chendeoxycholic acid Lithocholic acid 138. Multiple drug resistance of bacteria depends on which of the following: All of above Colicigenic factor (Col) Resistance transfer factor (RTF) Fertility factor (F +) 139. All of the following are formed via the cyclooxygenase pathway, except: Leukotrienes Thromboxanes Prostacyclin Prostaglandins 140. why fetal cells continue to divide but terminally differentiated adult cells do not divide there are many cyclin inhibitors which prevent cell from entering into S phase in adults phosphatase is absent in fetal cells absence of CD kinase proteinase is absent in fetus 141. Which of the following situations will lead to increased viscosity of blood amyloidogenesis multiple myeloma Fasting state Hypoglycemia 142. Windkessel effect in large arteries perform what function Prevent fluctuation in BP provide peripheral resistance Exchange of respiratory gases Maintain intravascular volume 143. Salivary amylase is activated by HCO3 Na+ Cl K+ 144. Eosinophils are characteristically seen in which of the following conditions? Parasitic infestations Fungal infections Viral infections Bacterial infections 145. First sensation to be lost in leprosy Touch Pain Temperature Pressure 146. Which of the following would shift the oxygen-hemoglobin dissociation curve to the right? Decreased pH Decreased temperature Decreased PCO2 Carbon monoxide poisoning 147. Which of the following bone malignancies is most fatal: Osteosarcoma Multiple myelorna Giant cell tumor Pagets disease 148. which of the following is absorbed in stomach salts fatty acids amino acids alcohols 149. Purkinje fibres are Modified cardiac muscle Modified smooth muscle Fibrous tissue Modified nerve fibres 150. an important non respiratory function of lungs is calcium balance sodium balance potassium balace anion balance 151. All of the following statements are true regarding reversible cell injury, except – Formation of blebs in the plasma membrane. Formation of amorphous densities in the mitochondrial matrix. Detachment of ribosomes from the granular endoplasmic reticulum. Diminished generation of adenosine triphosphate (ATP). 152. Wheel chair sign is seen in Thomson disease Beckers dystrophy Duchenne muscular dystrophy Parkinsonism 153. Schwannoma of spinal nerve roots is seen in Neurofibromatosis 1 Li-Fraumeni syndrome Turcot syndrome Neurofibromatosis 2 154. Not true of obstructive sleep apnea Spirometry is diagnostic Nocturnal asphyxia Alcoholism is a cofactor Prone to hypertension 155. Extrahepatic cholestasis causes: increase bilirubin in both urine and serum Increased urobilinogen in urine Increased urobilinogen in serum Increased bilirubin in urine 156. Diabetes mellitus affects all except: Brain Lung Kidney Heart 157. A decrease in which of the following parameters would tend to increase the glomerular capillary hydrostatic pressure? Bowman’s capsular hydrostatic pressure Efferent arteriolar resistance Afferent arteriolar resistance Capillary filtration coefficient 158. Investigation of choice to diagnose epilepsy Angiogram EEG MRI CT Scan 159. Actinomycetes is Fungus ram positive bacteria A yeast like form Gram negative bacteria 160. in a normal person which of the following occurs when he becomes supine from a standing position heart rate increases and settles to a higher level decreased perfusion at the apex of lung there is an immediate increase in venous return cerebral blood flow increases 161. The single most important laboratory test for determining the virulence of staphylococci is Hemolysis of sheep erythrocytes The catalase test Detection of coagulase Mannitol fermentation 162. Most common cause of Resistant hypertension is Obstructive sleep apnea Renovascular disease Pheochromocytoma Non compliance of patient 163. Cardiovascular effects seen in AIDS are all except CHF Pericardial tamponade Recurrent arterial embolism Aortic aneurysm 164. regarding transport of substances through the cell membrane all are true except glucose is transported via facilitated diffusion facilitated diffusion requires energy active transport is an energy deriven process facilitated diffusion requires carrier protein 165. all are second messengers ecept IP3 guanyl cyclise cAMP DAG 166. Most potent stimulator of naive T cells is: Follicular dendritic cells Macrophage Epithelial cells Immature dendritic cells 167. A 60 years old patient having cardiorespiratory arrest in hospital ward, for oxygenation what should be done immediately? Tracheostomy Oral intubation Cricothyroid membrane puncture Nasal intubation 168. Hematologic investigations of PT/INR are useful to detect defects in: Only extrinsic pathway lntrinsic and common pathway Extrinsic and common pathway Only intrinsic pathway 169. Not a characteristic of white infarct: Seen in soft tissue Involves wedge shaped area with apex pointing towards arterial obstruction Occurs due to arterial obstruction It can be transiently red 170. Causative organism for gas gangrene E. Coli Clostridium tetani Clostridium welchii Strep. Faecalis 171. Which type of necrosis listed below is the basic and most common type? Liquefactive necrosis Gaseous necrosis Gangrenous necrosis Coagulative necrosis 172. constitutive component of pulmonary endothelium cells plasminogen activator thrombin factor X lipoprotein lipase 173. Which is not seen in Cushing’ syndrome: Hypoglycemia Hypertension Osteoporosis Poor wound healing 174. Kidney stones (renal calculi) are a common complication in a patient with which disorder listed below? Hypopituitarism Hyperparathyroidism Hyperthyroidism Diabetes mellitus 175. In body plethysmography,a person is asked to expire against a closed glottis. What will be the change in the pressure in the lung and the box Increase in lung, decrease in box Decrease in both Decrease in lung, increase in box Increase in both 176. Blood transfusion associated acute lung injury occurs due to Genetic susceptibily HLA mediated Auto immune disorder Nosocomial infections 177. christmas disease occurs due to deficiency of factor XI factor VIII factor IX factor X 178. All are true regarding Donavanosis except: Syphilis can occur concomitant with it Endemic in tropical areas Causes painful ulcerative genital lesions The causative organism is Calymmatobacter granulomatis 179. Release of neurotransmitter from presynaptic vesicles is an example of Active transport Simple diffusion Exocytosis Facilitated diffusion 180. Phagocytosis enhanced by coating the surface of antigen is called Decoding CFT Opsonisation Chemotaxis 181. normal pH of stomach is 4 to 5 11 to 12 7 to 7.2 8 to 9 182. Difference in transudate and exudate is that the former has a: Cloudy appearance Low protein High protein Increased specific gravity 183. Best test for mycoplasma infection is CXR Culture of transtracheal aspirate gram stain of transtracheal aspirate PCR of respiratory secretions 184. maximum phosphate is reabsorbed in Loop of henle DCT Collecting duct PCT 185. All of the following infections may be transmitted by dental instruments except HIV Hepatitis E Hepatitis C Hepatitis B 186. Tumor lysis syndrome is characterized by all except: Hyperuricemia Hyperphosphatemia Hypercalcemia Hyperkalemia 187. The exact part of the antigen that reacts with the immune system is called as Idiotope Epitope Paratope Clone 188. Virchow’s triad consists of all except: Endothelial injury Vascular stasis Hypercoagulability Platelet plug 189. Techoic acid is present in Cytoplasm of Gram positive organisms Cell wall of Gram negative organisms Cell wall of Gram positive organisms Cytoplasm of Gram negative organisms 190. During normal diastole, which of the following is most important in preventing over- distension of the ventricles? Adjacent lungs Fibrous pericardium Aortic valve Diaphragm 191. A child on administration of Penicillin developed fever, rashes, urticaria and swelling. It is due to: Delayed hypersensivity Immune complex cytotoxicity Ig G mediated hypersensitivity Ig E mediated hypersensitivity 192. Continuous murmur is seen in all of the following conditions except PDA Pulmonary AV fistula Coronary AV fistula VSD with aortic regurgitation 193. The oxygen-hemoglobin dissociation curve shifts to the left under which of the following circumstances? Increased 2,3-diphosphoglycerate (2,3-DPG) D. Increased PCO2 Increased temperature Decreased pH Carbon monoxide poisoning 194. Vagal stimulation of the heart causes decrease in heart rate by Decrease in action potential spike Increase in repolarisation Decrease in slope of prepotential Decrease conduction 195. life span of RBC is 3 years 1 year 100 days 14 days 196. interference with oxygen exchange in lungs is a type of histotoxic hypoxia hypoxic hyoxia anoxic anoxia anoxemia 197. Consider two patients with atherosclerosis, one is diabetic and other is non-diabetic. When compare to non-diabetic, diabetic patient has hundred times increased risk of Myocardial infarction Stroke Lower limb ischemia vertebro basilar insufficiency 198. Acute infection causes: Leucocytosis Monocytosis Neutropenia Leucopenia 199. You have to draw blood from a patient. When will you give EDTA? EDTA is not an anticoagulant Through I.V. route before drawing blood Orally starting several days before EDTA will be added in test tube 200. A patient in emergency with symptoms of tachycardia bronchodilation increased temperature and constipation .He may be suffering from poisoning with Mushroom Atropine Penicillamine Organophosphorus 201. Episodic generalized weakness is related to all except: Hypocalcemia Hypophosphatemia Hypokalemia Hyponatremia 202. Which of the following does not occur as the blood passes through systemic capillaries Increased hematocrit Shift of haemoglobin dissociation curve to left increased protein content Decreased pH 203. The following hepatitis virus is transmitted by faeco-oral route: except Hepatitis C Virus Hepatitis B Virus Hepatitis D Virus Hepatitis E Virus 204. maximum water reabsorption in the GIT occurs in stomach jejunum ileum colon 205. Tuberculin test screens for Phagocyte dysfunction Complement function Cell mediated immunity Humoral immunity 206. Effusion in TB is characterized by: Protein >3 gm/dL Effusion LDH/Serum LDH= < 0.6 High glucose Few cells, 207. Which of these is true about antibodies: Secretory part of IgA is synthesized by plasma cells IgE mediated delayed hypersensitivity IgM is seen in secondary response IgM is an acute phase reactant 208. Blood pressure is difficult to measure in a patient with Mitral stenosis Aortic stenosis Atrial fibrillation Complete heart block 209. Which of the following regions of the nephron is capable of the greatest level of glucose reabsorption? Collecting duct Proximal convoluted tubule Distal convoluted tubule Thick ascending limb of loop of henle 210. physiolgical response to smoking are all except increased hematocrit decreased carboxyhemoglobin decreased HDL increased heart rate and increased catecholemine release 211. Regarding leptospirosis all are true except: Humans are accidental hosts of the disease Lice act as reservoirs of disease It is a zoonosis Humans are the end hosts 212. Doppler ultrasound, all are true except? Monophasic tracing measure normal flow Direction of blood flow Degree of stenosis Provide information about blood velocity 213. The mechanism of genetic transfer where a phage serves as a vehicle Is Lysogeny Translation Conjugation Transformation 214. Hockey stick appearance in echocardiography is a feature of Aortic regurgitation Aortic stenosis Mitral stenosis Mitral incompetence 215. All of the following drugs are used in pituitary adenoma except Octreotide Letrozol Bromocryptine Orlistat 216. The best way to sterilize an instrument soaked in AIDS virus is: Clean and autoclave with dry heat Boiling for 1 hour Dip the instrument in glutaraldehyde Moist autoclaving 217. If diameter of a vessel is doubled Blood flow decreases sixteen fold Blood flow decreases four fold Blood flow increases sixteen fold Blood flow increases four fold 218. A patient is admitted in casualty with signs of fever, lymphadenopathay etc. Investigations reveal infection by pseudomonas aeruginosa. Drug of choice includes Piperacillin + Tazobactam Cefalexin Doxycycline Ceftriaxone 219. Acute infection causes: Neutropenia Leucocytosis Leucopenia Monocytosis 220. Mid systolic click is classically heard in Hamman-rich syndrome Rheumatic aortic regurgitation Congenital Mitral stenosis Mitral valve prolapsed 221. APGAR score is a quantitative method of assessing score of new born status based on Neurologic,renal and respiratory Neurologic,digestive and respiratory Neurologic,circulatory and renal Neurologic ,circulatory and respiratory 222. Nucleus in reticulocyte is: Fragmented Absent Compact Pyknotic 223. in a healthy patient the spaces between the body contain fibrous connective tissue water air loose connective tissue 224. Percentage of Total body water to total body weight at birth is 50 percentage 60 percentage 90 percentage 80 percentage 225. If a creatinine clearance of 100 mL/min changes to 50 mL/min over 1 year, assuming that there has been no change in diet, which of the following physiologic changes can be expected? 2-fold decrease in blood urea nitrogen concentration A 2-fold increase in creatinine excretion rate A 2-fold increase in plasma creatinine concentration A 2-fold decrease in creatinine excretion rate 226. Antigenieity is seen in: Golgi bodies Nuclear membrane Phospholipids Cardiolipin 227. Cytokines are soluble proteins secreted by which of the following cells? Macrophages All of the above Fibroblasts Lymphocytes 228. The most important parameter to monitor Dengue haemorrhagic fever is Haemoglobin Platelet count Total leucocyte count Haematocrit 229. maximum potassium ions secretion is seen in gastric secretion colonic secretions saliva jejunal secretion 230. A protoplast is best described as a bacterial cell Containing a cell wall and a capsule With a cell wall but free of capsule Uniquely sensitive to penicillin Free of cell wall and capsule 231. Insulin resistant DM: All DM are sensitive to insulin Type II Juvenile onset Type I 232. normal anion gap is (in mEq/l) 25 to 30 10 to 12 18 to 20 3 to 5 233. the sigmoid nature of Hb-O2 dissociation curve is because of alpha chain has more affinity for O2 than beta chain hemoglobin is acidic in nature beta chain has more affinity for alpha chain binding of one O2 molecule increase the affinity for the next O2 molecule 234. Hemophilia A is caused by defect of gene encoding: Factor 8 Factor 13 Factor 9 Factor 5 235. Opacity around colonies of Clostridium perfringens is due to – Cytokinin Desmotase Theta toxin Lecithinase 236. H. pylori infection is seen in all except: Gastric carcinoma Fundal gastritis Gastric lymphoma Duodenal ulcer 237. Antibiotic sensitivity and resistance of microorganisms is determined by DNA probe Culture ELISA Direct microscopy 238. With regards to temperature requirement, most pathogenic bacteria are: Mesophiles Ciyophiles Thermophites Psychrophiles 239. Sulfonylureas acts by: Ca+2 channel activation Activating DPP-4 K+ channel closure Increasing cell sensitivity 240. Nitrogen washout method is used for estimating Tidal volume Functional residual capacity Diffusion capacity Dead space volume Loading …
